System for conditioning surfaces in vivo
A system and method for conditioning surfaces of a body in vivo includes providing an electrical energy source, coupling the electric energy source to the surface, and delivering electropositive current from the electrical energy source to the surface so as to generate a sub-threshold current density on the surface. In preferred embodiments, the sub-threshold electropositive current density is between about 0.001 and about 1.0 mA/cm 2 .
1. A medical device comprising:
a blood contacting surface having an electropositive current density of between about 0.001 and about 1.0 mA/cm 2 ; wherein the blood contacting surface inhibits thrombogenesis.
2. The medical device of claim 1 wherein the medical device is an implantable medical device.
3. The medical device of claim 1 wherein the medical device is a prosthetic heart valve.
4. The medical device of claim 1 wherein the blood contacting surface is a valve leaflet.
5. The medical device of claim 1 wherein the medical device is a stent.
6. The medical device of claim 1 wherein the blood contacting surface inhibits blood platelet adhesion.
7. The medical device of claim 1 further comprising an electrical energy source delivering between about 0.1 and about 10 mA electropositive current to the blood contacting surface.
8. The medical device of claim 7 wherein the electrical energy source is an implantable electrical energy source.
9. The medical device of claim 7 wherein the electrical energy source is an extra-corporal electrical energy source.