IP Library › Patent Application 15820959
Patent Application
App. No. 15/820,959

PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE

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Quick Facts
Patent No.
US None
App. No.
15/820,959
Abstract

The present invention is concerned with novel processes for the preparation of (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof. These compounds have pharmaceutical utility and are known to be useful for treating e.g., depression, anxiety disorders, eating disorders and urinary incontinence.

Claims (19)

1 - 13 . (canceled)

14 . A compound selected from the group consisting of:

or a salt thereof.

15 . The compound of claim 14 , wherein the compound is

or a salt thereof.

16 . The compound of claim 14 , wherein the compound is

or a salt thereof.

17 . A compound selected from the group consisting of:

or a salt thereof.

18 . The compound of claim 17 , wherein the compound is

or a salt thereof.

19 . The compound of claim 17 , wherein the compound is

or a salt thereof.

20 . A compound selected from the group consisting of:

or a salt thereof.

21 . The compound of claim 20 , wherein the compound is

or a salt thereof.

22 . The compound of claim 20 , wherein the compound is

or a salt thereof.

Assignments (4)
MERGER AND CHANGE OF NAME Recorded Nov 6, 2018
From: DOV PHARMACEUTICAL, INC.; DOV PHARMACEUTICAL, INC.
To: EUTHYMICS BIOSCIENCE, INC.
Reel/Frame 047431/0630 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2018
From: MURRY, JERRY A.; SIMMONS, BRYON; CORLEY, EDWARD G.; XU, FENG
To: MERCK & CO., INC.
Reel/Frame 045333/0581 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2018
From: MERCK & CO., INC.
To: DOV PHARMACEUTICAL, INC.
Reel/Frame 045688/0587 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2018
From: EUTHYMICS BIOSCIENCE, INC.
To: ETHISMOS RESEARCH, INC.
Reel/Frame 045252/0870 →