IP Library Granted Patent US 10,544,088
Granted Patent B2
US 10,544,088 · App. 15/828,700 · Granted Jan 28, 2020

Pharmaceutically acceptable salts of fatty acids

Inventors: Mehar Manku (Birmingham, GB); David Coughlan (Dublin, IE); Bill Downes (Dublin, IE)
Assignee: DS Biopharma Limited
C07C229/26A61K31/202C07C59/42C07C215/10C07D295/027C07C241/04
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Quick Facts
Patent No.
US 10,544,088
App. No.
15/828,700
Granted
Jan 28, 2020
Kind
B2
Abstract

The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising same and methods of making and using same.

Claims (3)

1. A method of treating a skin inflammation, acne or erythema in a subject in need thereof, the method comprising administering to the subject a pharmaceutical composition comprising a lysine salt form of 15-hydroxy-8(Z),11(Z),13(E)-eicosatrienoic acid (15-HETrE).

2. The method of claim 1 , wherein the pharmaceutical composition further comprises an excipient.

3. The method of claim 1 , wherein the pharmaceutical composition is administered topically.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 13, 2018
From: MANKU, MEHAR; DOWNES, BILL; COUGHLAN, DAVID
To: DIGNITY SCIENCES LIMITED
Reel/Frame 046075/0599 →
CHANGE OF NAME Recorded Jun 13, 2018
From: DIGNITY SCIENCES LIMITED
To: DS BIOPHARMA LIMITED
Reel/Frame 046075/0622 →
Continuity (3)
Continuation 14543638 · Nov 17, 2014
Provisional Application 61904600 · Nov 15, 2013
Related Publication 20180118655A1 · May 3, 2018