IP Library Granted Patent US 11,197,917
Granted Patent B2
US 11,197,917 · App. 15/829,703 · Granted Dec 14, 2021

Formulations for nutritional support in subjects in need thereof

Inventors: Ron Belldegrun (New York, NY); Mia Funt (New York, NY)
Assignee: ByHeart, Inc.
A61K38/40A23L33/115A23L33/125A23L33/19A23L33/40A61K9/0095A61K38/018A61K38/19A61K38/38A23V2002/00
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Quick Facts
Patent No.
US 11,197,917
App. No.
15/829,703
Granted
Dec 14, 2021
Kind
B2
Abstract

Formulations having a protein component, in which the protein contains one or more digestion-aiding proteins, and/or one or more immunoprotective proteins. The formulations may also contain a fat component, a carbohydrate component, and vitamins and minerals. These formulations can be used to provide nutritional support to a subject, either as dietary supplements or as a primary source of nutrition, such as for an infant formula.

Claims (21)

1. A formulation for oral administration comprising a protein component, the protein component designating the entire amount of protein comprised by the formulation, wherein the protein component comprises:

(a) one or more digestion-aiding proteins, comprising whey protein hydrolysate (WPH), and alpha-lactalbumin; and

(b) one or more immunoprotective proteins, comprising lactoferrin;

wherein the one or more digestion-aiding proteins and the one or more immunoprotective proteins comprise about 15% to about 75% by weight of the protein component;

wherein the WPH comprises 26% to 35% by weight of the protein component;

wherein the alpha-lactalbumin comprises 14% to 20% by weight of the protein component;

wherein the lactoferrin comprises 1% to 6% by weight of the protein component;

wherein the formulation comprises a milk component comprising whole cow's milk;

wherein the milk component comprises milk protein naturally occurring in the whole cow's milk, the entire amount of the milk protein being considered part of the protein component; and

wherein the whole cow's milk is in an amount to provide 25% to 30% by weight of the protein component.

2. A formulation for oral administration comprising a protein component, a fat component, a carbohydrate component, and whole milk, wherein:

(a) the protein component, designating the entire amount of protein comprised by the formulation, including protein naturally occurring in the milk, comprises whey protein hydrolysate (WPH), alpha-lactalbumin, and lactoferrin, wherein the WPH comprises 26% to 35% by weight of the protein component, the alpha-lactalbumin comprises 14% to 20% by weight of the protein component, and the lactoferrin comprises 1% to 6% by weight of the protein component;

(b) the fat component comprises one or more vegetable oils, one or more plant oils, or a combination thereof;

(c) the carbohydrate component comprises lactose and galactooligosaccharide; and

(d) the whole milk is in an amount to provide 25% to 30% by weight of the protein component.

3. The formulation of claim 2 , wherein:

the WPH comprises 26% to 28% of the protein component; and

the alpha-lactalbumin comprises 18% to 20% of the protein component.

4. The formulation of claim 2 , wherein:

the WPH and the lactoferrin are present in the formulation in a ratio of 3:1 to 7:1 by weight; and

the alpha-lactalbumin and the lactoferrin are present in the formulation in a ratio of 2:1 to 4:1 by weight.

Assignments (6)
RELEASE OF SECURITY INTEREST IN PATENTS AT R/F 74336/0782 Recorded Jul 13, 2026
From: POLARIS PARTNERS X, L.P. AS SECOND LIEN ADMINISTRATIVE AGENT
To: BYHEART, INC.
Reel/Frame 075986/0317 →
SECOND LIEN PATENT SECURITY AGREEMENT Recorded Jan 14, 2026
From: BYHEART, INC.
To: POLARIS PARTNERS X, L.P., AS ADMINISTRATIVE AGENT
Reel/Frame 074336/0782 →
CORRECTIVE ASSIGNMENT TO CORRECT THE TYPOGRAPHICAL ERROR IN U.S. PATENT NO. 11,197,917 IN THE ASSIGNMENT COVER SHEET PREVIOUSLY RECORDED ON REEL 71733 FRAME 776. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST. Recorded Nov 21, 2025
From: BYHEART, INC.
To: OAKTREE FUND ADMINISTRATION, LLC
Reel/Frame 073660/0473 →
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL/FRAME 064566/0437 Recorded Jul 16, 2025
From: PERCEPTIVE CREDIT HOLDINGS IV, LP
To: BYHEART, INC.
Reel/Frame 072002/0439 →
SECURITY INTEREST Recorded Aug 11, 2023
From: BYHEART, INC.
To: PERCEPTIVE CREDIT HOLDINGS IV, LP
Reel/Frame 064566/0437 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2021
From: BELLDEGRUN, RON; FUNT, MIA
To: BYHEART, INC.
Reel/Frame 057595/0686 →
Continuity (1)
Related Publication 20190167766A1 · Jun 6, 2019