IP Library › Granted Patent US 10,220,050
Granted Patent B2
US 10,220,050 · App. 15/835,088 · Granted Mar 5, 2019

Isotopologues of 5-azacytidine

Inventors: John F. Traverse (Lebanon, NJ); William W. Leong (Westfield, NJ); Jeffrey B. Etter (Boulder, CO); Mei Lai (Longmont, CO); Jay Thomas Backstrom (Leawood, KS)
Assignee: Celgene Corporation
A61K31/706A61K9/2013A61K9/2018A61K9/2846A61K9/2866A61K9/2886A61K31/7068A61K47/10
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Quick Facts
Patent No.
US 10,220,050
App. No.
15/835,088
Granted
Mar 5, 2019
Kind
B2
Abstract

The present disclosure provides isotopologues of 5-azacytidine.

Claims (3)

1. A compound of the formula:

or a pharmaceutically acceptable salt thereof, wherein:

Y 6 is a hydrogen isotopically enriched with deuterium, and Y 1 , Y 2 , Y 3 , Y 4 , Y 5 , and are non-enriched hydrogen atoms.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2019
From: ETTER, JEFFREY B.; LAI, MEI; BACKSTROM, JAY THOMAS; TRAVERSE, JOHN F.; LEONG, WILLIAM W.
To: CELGENE CORPORATION
Reel/Frame 047935/0202 →
Continuity (7)
Division 14788606 · Jun 30, 2015
Continuation 14463424 · Aug 19, 2014
Continuation 12466213 · May 14, 2009
Provisional Application 61157875 · Mar 5, 2009
Provisional Application 61201145 · Dec 5, 2008
Provisional Application 61053609 · May 15, 2008
Related Publication 20180153916A1 · Jun 7, 2018