IP Library Granted Patent US 11,191,588
Granted Patent B2
US 11,191,588 · App. 15/844,050 · Granted Dec 7, 2021

Methods for evaluating the integrity of a uterine cavity

Inventors: Akos Toth (Cupertino, CA); Robin Bek (Campbell, CA); Dominique Filloux (Redwood City, CA); Tejas N. Mazmudar (Palo Alto, CA); Csaba Truckai (Saratoga, CA)
Assignee: Minerva Surgical, Inc.
A61B18/1485A61B2018/0022A61B2018/00232A61B2018/00559A61B2018/00642A61B2018/00702A61B2018/00744A61B2018/00791A61B2018/00821A61B2018/00863
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Quick Facts
Patent No.
US 11,191,588
App. No.
15/844,050
Granted
Dec 7, 2021
Kind
B2
Abstract

Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO 2 ) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

Claims (23)

1. A method of characterizing a patient's uterus, the method comprising:

positioning an expandable structure in a patient's uterine cavity, the expandable structure comprising a portion of an energy application system for delivering ablation energy to uterine tissue;

expanding the expandable structure within the uterine cavity;

introducing a gas into the uterine cavity exterior of expandable structure expanded within the uterine cavity;

introducing a gas into the expandable structure as the expandable structure expands;

monitoring a flow rate of the gas introduced into the expandable structure as the expandable structure expands;

monitoring a flow rate of the gas introduced into the uterine cavity exterior of the expandable structure as the expandable structure expands; and

determining whether the uterine cavity is perforated or non-perforated based on the monitored flow rate of the gas introduced into the expandable structure and the monitored flow rate of the gas introduced into the uterine cavity exterior of the expandable structure,

wherein the uterine cavity is determined as perforated if the flow rate of the gas introduced into the expandable structure impinges the flow rate of the gas introduced into the uterine cavity exterior of the expandable structure.

2. The method of claim 1 wherein the positioning step comprises transcervically introducing a probe into the uterine cavity, the probe carrying the expandable structure.

3. The method of claim 1 wherein the gas introduced into the uterine cavity is CO2.

4. The method of claim 1 wherein the gas introduced into the expandable structure is Argon.

5. The method of claim 1 wherein the flow rate of the gas introduced into the uterine cavity impinges the flow rate of the gas introduced into the uterine cavity exterior of the expandable structure if the flow rate of the gas introduced into the uterine cavity changes during the introduction of the gas into the expandable structure.

6. The method of claim 1 wherein the flow rates of the gas introduced into the expandable structure and the introduced into the uterine cavity exterior of the expandable structure are monitored contemporaneously.

7. The method of claim 1 wherein the flow rates of the gas introduced into the expandable structure and the introduced into the uterine cavity exterior of the expandable structure are monitored sequentially.

8. The method of claim 7 including the flow rate of the gas introduced into the uterine cavity is monitored first and then the flow rate of the gas introduced into the expandable structure is monitored.

9. The method of claim 8 , wherein the flow rate of the gas introduced into the expandable structure is monitored 2 seconds after the flow rate of the gas introduced into the uterine cavity is monitored.

10. The method of claim 7 including the flow rate of the gas introduced into the expandable structure is monitored first and then the flow rate of the gas introduced into uterine cavity is monitored.

11. The method of claim 1 wherein the flow rate of the gas introduced into the uterine cavity is monitored at least twice.

12. The method of claim 1 wherein the flow rate of the gas introduced into the expandable structure is monitored at least twice.

13. The method of claim 1 wherein the gas is introduced into the expandable structure at a flow rate of 0.8 SLPM.

14. The method of claim 1 wherein the expanding of the expandable structure within the uterine cavity comprises expanding a frame in an interior chamber of the expandable structure.

15. The method of claim 14 further comprising applying a negative pressure to an interior chamber of the expandable structure to suction an expandable thin wall sheath against the frame.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 12, 2026
From: MINERVA SURGICAL, INC.
To: AXORA MEDICAL, INC.
Reel/Frame 075561/0186 →
RELEASE OF SECURITY INTEREST Recorded Feb 5, 2026
From: CANADIAN IMPERIAL BANK OF COMMERCE
To: MINERVA SURGICAL, INC.
Reel/Frame 074721/0585 →
SECURITY INTEREST Recorded Jan 30, 2026
From: AXORA MEDICAL, INC.
To: SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AGENT AND COLLATERAL AGENT
Reel/Frame 074537/0617 →
SECURITY INTEREST Recorded Oct 8, 2021
From: MINERVA SURGICAL, INC.
To: CANADIAN IMPERIAL BANK OF COMMERCE
Reel/Frame 057758/0137 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2017
From: TOTH, AKOS; BEK, ROBIN; FILLOUX, DOMINIQUE; MAZMUDAR, TEJAS N.; TRUCKAI, CSABA
To: MINERVA SURGICAL, INC.
Reel/Frame 044410/0983 →
Continuity (5)
Continuation 13488214 · Jun 4, 2012
Continuation 13442449 · Apr 9, 2012
Provisional Application 61491842 · May 31, 2011
Provisional Application 61483542 · May 6, 2011
Related Publication 20180103999A1 · Apr 19, 2018
Cited By (1)
US 12,402,938