IP Library Granted Patent US 10,583,250
Granted Patent B2
US 10,583,250 · App. 15/870,674 · Granted Mar 10, 2020

System and method for adjusting insulin delivery

Inventors: Bryan Mazlish (Palo Alto, CA); Lane Desborough (Thousand Oaks, CA); Ross Naylor (Fullerton, CA)
Assignee: Bigfoot Biomedical, Inc.
A61M5/1723A61B5/14532A61B5/4839A61M5/14248A61M5/31568G16H20/17G16H40/63A61K38/28A61M5/003A61M2205/3379A61M2205/35A61M2205/3569A61M2205/3584A61M2205/502A61M2205/52A61M2205/8206A61M2230/201
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Quick Facts
Patent No.
US 10,583,250
App. No.
15/870,674
Granted
Mar 10, 2020
Kind
B2
Abstract

The embodiments described herein may relate to methods and systems for adjusting insulin delivery. Some methods and systems may be configured to adjust insulin delivery to personalize automated insulin delivery for a person with diabetes. Such personalization may include adjusting user specific dosage parameters in response to one or more back-filled time segments associated with a diurnal time block.

Claims (27)

1. A method comprising:

determining available insulin delivery segments for a back-fill time based on a correction bolus;

determining a cumulative insulin on board (IOB) based on all the available insulin delivery segments being back-filled;

back-filling a number of the available insulin delivery segments;

adjusting the number of the available insulin delivery segments that are back-filled until one of the cumulative IOB based on the number of back-filled insulin delivery segments is equal to or less than the correction bolus, or the cumulative insulin of the number of back-filled insulin delivery segments is less than the correction bolus; and

adjusting a baseline basal rate based on the back-filled insulin delivery segments, the baseline basal rate used for a diurnal time block related to at least a portion of the back-fill time.

2. The method of claim 1 , wherein the correction bolus is a negative bolus.

3. The method of claim 1 , further comprising configuring an insulin delivery system to deliver insulin during the diurnal time block based on the adjusted baseline basal rate.

4. The method of claim 3 , further comprising delivering insulin during the diurnal time block based on the adjusted baseline basal rate.

5. The method of claim 1 , wherein the diurnal time block is for a same time of day that covers the portion of the back-fill time on a day later than when the correction bolus is delivered.

6. The method of claim 1 , further comprising adjusting one or both of a carbohydrate-to-insulin ratio and an insulin sensitivity factor for the diurnal time block.

7. The method of claim 1 , wherein back-filling the number of available insulin delivery segments comprises adjusting at least one insulin delivery action associated with each of the number of available insulin delivery segments.

8. The method of claim 7 , wherein the at least one insulin delivery action comprises delivering a dose of insulin that is a multiple or a fraction of a baseline basal insulin.

9. The method of claim 8 , further comprising updating historical insulin delivery information based on one or more insulin delivery actions associated with the adjusted number of available insulin delivery segments.

10. A system comprising:

an insulin delivery device configured to deliver insulin via a plurality of insulin delivery actions over a back-fill time prior to a correction bolus, and deliver the correction bolus; and

a control device in communication with the insulin delivery device, the control device configured to:

obtain an amount of insulin delivered in the correction bolus;

determine available insulin delivery segments for the back-fill time based on which of the plurality of insulin delivery actions delivered less than a maximum amount of insulin relative to a baseline basal rate;

back-fill a number of the available insulin delivery segments based on an amount of insulin in the correction bolus; and

adjust a baseline basal rate based on the back-filled insulin delivery segments, the baseline basal rate used for a diurnal time block related to at least a portion of the back-fill time.

11. The system of claim 10 , wherein the insulin delivery device delivers insulin during the diurnal time block based on the adjusted baseline basal rate.

12. The system of claim 10 , further comprising a user interface, wherein the user interface is configured to display historical insulin delivery information.

13. The system of claim 12 , wherein the user interface is configured to update displayed historical insulin delivery information based on one or more insulin delivery actions associated with the number of available insulin delivery segments.

14. The system of claim 13 , wherein at least one of the one or more insulin delivery actions is associated with delivering a dose of insulin that is a multiple or a fraction of baseline basal insulin.

15. The system of claim 10 , further comprising personalizing the delivery of insulin for a diurnal time period by adjusting one or both of a carbohydrate-to-insulin ratio and an insulin sensitivity factor for the diurnal time block,

wherein the personalizing is completed after delivering the correction bolus.

Assignments (16)
SECURITY INTEREST Recorded Jan 10, 2025
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069870/0519 →
SECURITY INTEREST Recorded Jan 10, 2025
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069870/0456 →
SECURITY INTEREST Recorded Sep 30, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069074/0001 →
SECURITY INTEREST Recorded Sep 30, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069073/0912 →
SECURITY INTEREST Recorded Sep 24, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069030/0104 →
SECURITY INTEREST Recorded Sep 24, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069030/0296 →
SECURITY INTEREST Recorded Sep 23, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 069019/0142 →
SECURITY INTEREST Recorded Sep 23, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 069019/0188 →
SECURITY INTEREST Recorded Sep 12, 2024
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 068948/0324 →
SECURITY INTEREST Recorded Sep 12, 2024
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 068948/0172 →
SECURITY AGREEMENT SUPPLEMENT Recorded Sep 7, 2023
From: INSULET CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 064840/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2023
From: BIGFOOT BIOMEDICAL, INC.
To: INSULET CORPORATION
Reel/Frame 062900/0001 →
RELEASE OF SECURITY INTEREST Recorded Feb 17, 2023
From: MADRYN FUND ADMINISTRATION, LLC
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 062793/0316 →
SECURITY INTEREST Recorded Feb 10, 2023
From: MADRYN HEALTH PARTNERS, LP
To: MADRYN FUND ADMINISTRATION, LLC
Reel/Frame 062702/0145 →
SECURITY INTEREST Recorded Mar 12, 2021
From: BIGFOOT BIOMEDICAL, INC.
To: MADRYN HEALTH PARTNERS, LP
Reel/Frame 055583/0044 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 9, 2018
From: MAZLISH, BRYAN; DESBOROUGH, LANE; NAYLOR, ROSS
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 047104/0020 →
Cited By (31)
US 12,226,612 US 12,296,139 US 12,303,667 US 12,303,668 US 12,318,577 US 12,343,502 US 12,370,307 US 12,370,309 US 12,383,166 US 12,406,760 US 12,431,229 US 12,485,223 US 12,495,994 US 12,496,398 US 12,514,979 US 12,514,980 US 12,521,486 US 12,551,619 US 12,558,026 US 12,562,251 US 12,564,679 US 12,569,619 US 12,592,306 US 12,636,435 US 12,646,601 US 12,651,659 US 12,653,949 US 12,667,665 US 12,691,221 US 12,691,222 US 12,708,709