Granted Patent B2

US 12,496,398 · App. 17/824,494 · Granted Dec 16, 2025

Inventors: Ashutosh Zade (San Diego, CA); Joon Bok Lee (Acton, MA); Yibin Zheng (Hartland, WI)

Assignee: INSULET CORPORATION

A61M5/1723A61B5/14532A61B5/4839A61M5/14248G16H20/17G16H40/63A61M2005/14208A61M2205/52A61M2230/201

Abstract

Claims (66)

1 . A wearable drug delivery device, comprising:

a processor;

a memory storing an automatic glucose control application, programming code, and data related to the automatic glucose control application;

a reservoir shaped to contain a liquid drug;

a pump mechanism controlled by the processor and operable to deliver the liquid drug; and

a communication circuit controlled by the processor and operable to communicate with an external device, wherein:

the processor when executing the automatic glucose control application is operable to:

for a period of time, receive blood glucose measurement values at a first set time interval within the period of time;

determine a rate of change of the blood glucose measurement values received from an analyte sensor over the period of time; and

based on the determined rate of change, select a second set time interval different than the first set time interval.

2 . The wearable drug delivery device of claim 1 , wherein the processor, when determining the rate of change of blood glucose measurement values over the period of time, is further operable to:

utilize a sample threshold equation to determine whether a rate of change between blood glucose measurement values at different times exceeds a sample threshold value.

3 . The wearable drug delivery device of claim 1 , wherein the processor, when determining the rate of change of blood glucose measurement values over the period of time, is further operable to:

utilize several samples in a sample threshold equation to determine whether a rate of change between blood glucose measurement values at different times exceeds a sample threshold value.

4 . The wearable drug delivery device of claim 1 , wherein the processor receives the blood glucose measurement value from an analyte sensor remote from the wearable drug delivery device at the set time interval.

5 . The wearable drug delivery device of claim 1 , wherein the processor when selecting the different set time interval is operable to:

choose the different set time interval from a table, wherein the table is based on the determined rate of change, wherein the different set time interval is a set time value that is half, one third, one quarter or one fifth of the set time interval.

6 . The wearable drug delivery device of claim 1 , wherein the processor when selecting the different set time interval is operable to:

calculate the different set time interval based on the determined rate of change and the set time interval by dividing the set time interval by a constant.

7 . The wearable drug delivery device of claim 1 , wherein the processor is further operable to:

after selection of the different set time interval, setting the different set time interval to the set time interval for future receipt of blood glucose measurement values at the set time interval.

8 . The wearable drug delivery device of claim 1 , wherein the communication circuit is further operable to:

establish, in response to a control signal from the processor, a communication session with an analyte sensor remote from the wearable drug delivery device; and

receive the blood glucose measurement value during the communication session, wherein the communication session is established to enable receipt of the blood glucose measurement value at the set time interval.

9 . The wearable drug delivery device of claim 1 , wherein the period of time spans multiple set time intervals.

10 . The wearable drug delivery device of claim 1 , wherein the processor when selecting the different set time interval is operable to:

calculate the different set time interval based on the determined rate of change and the set time interval by dividing the set time interval by a constant.

11 . An analyte sensor, comprising:

logic circuitry;

a sensor coupled to the logic circuitry and operable to determine an analyte measurement value from a blood sample of a user, wherein the sensor is further operable to make the determination of the analyte measurement value at a set detection rate of the sensor; and

a communication circuit coupled to the logic circuitry and operable to transmit a signal containing the determined analyte measurement value, wherein the logic circuitry is operable to:

control the sensor including setting the detection rate of the sensor based on a selection from multiple detection rates,

obtain the analyte measurement value from the sensor,

determine a rate of change of analyte measurement values received over a period of time;

based on the determined rate of change, determine that delivery of a liquid drug is to be suspended;

generate a suspension signal; and

cause the communication circuit to transmit the suspension signal.

12 . The analyte sensor of claim 11 , wherein the logic circuitry is further operable to:

provide, based on the set detection rate, the analyte measurement value to the communication circuit to be transmitted by the communication circuit.

13 . The analyte sensor of claim 11 , wherein the logic circuitry, when determining the rate of change is further operable to:

retrieve past analyte measurement values in a memory coupled to the logic circuitry;

analyze the analyte measurement value with reference to the past analyte measurement values stored in the memory;

determine an updated rate of change of the analyte measurement value and the past analyte measurement values;

determine that the updated rate of change the analyte measurement value and the past analyte measurement values exceeds a sample threshold; and

in response to the updated rate of change the analyte measurement value and the past analyte measurement values exceeding the sample threshold, cause the generation of the suspension signal.

14 . The analyte sensor of claim 11 , wherein the logic circuitry is further operable to:

determine a negative rate of change of the analyte measurement values; and

in response to the determined negative rate of change, increase the detection rate of the sensor.

15 . The analyte sensor of claim 14 , wherein the logic circuitry is further operable to:

in response to the increased detection rate of the sensor, cause the communication circuit to output analyte measurement values at a rate matching the increased detection rate of the sensor a result of a detection of the analyte measurement value from the blood sample of the user to an external device.

16 . The analyte sensor of claim 11 , wherein the logic circuitry is further operable to:

determine a positive rate of change of the analyte measurement values; and

in response to the determined negative rate of change, decrease the detection rate of the sensor.

17 . The analyte sensor of claim 16 , wherein the logic circuitry is further operable to:

in response to the decreased detection rate of the sensor, cause the communication circuit to output at a rate matching the decreased detection rate of the sensor a result of a detection of the analyte measurement value from the blood sample of the user to an external device.

18 . A wearable medical device, comprising:

a processor or logic circuitry; and

a memory storing instructions that, when executed by the processor or logic circuitry, configure the wearable medical device to:

determine that an event affecting a blood glucose measurement value trend of a user has occurred;

based on the occurrence of the event, select a mode of operation of an analyte sensor; and

generate a signal indicating the selected mode of operation of the analyte sensor.

19 . The wearable medical device of claim 18 , further comprising:

a communication device coupled to the processor, wherein the processor is further operable to:

output the generated signal indicating the selected mode of operation to a continuous glucose monitor that is communicatively coupled to the processor.

20 . The wearable medical device of claim 18 , wherein the processor, when selecting the mode of operation of the analyte sensor based on the occurrence of the event is further operable to:

request an on-demand reading by the analyte sensor when the event is determined to be a meal event or a large meal bolus event.

Assignments (2)

Continuity (2)

References Cited (400)