IP Library Granted Patent US 10,675,461
Granted Patent B2
US 10,675,461 · App. 15/885,365 · Granted Jun 9, 2020

Functional electrical stimulation

Inventors: Anthony M J Bull (London, GB); Lance Rane (London, GB)
Assignee: Imperial College Innovations Limited
A61N1/36003A61N1/36021
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Quick Facts
Patent No.
US 10,675,461
App. No.
15/885,365
Granted
Jun 9, 2020
Kind
B2
Abstract

Methods of treatment of disorders of the knee, such as medial osteoarthritis and knee instability due to anterior cruciate ligament deficiency, are provided herein.

Claims (34)

1. A method of treating medial knee joint pain during gait in a patient in need thereof, the method comprising the following steps during gait:

a) applying functional electrical stimulation to one or more of the gluteus medius, biceps femoris or gastrocnemius of the leg in need of treatment prior to foot strike of the foot of the leg in need of treatment;

b) maintaining functional electrical stimulation to the muscle(s) stimulated in step a) for the period of stance of the leg in need of treatment;

c) ceasing functional electrical stimulation of the muscle stimulated in step a) at the end of the period of stance of the leg in need of treatment;

d) optionally repeating steps a) to c) in respect of the corresponding muscle(s) of the patient's other leg; and

e) repeating steps a) to d) for each stride of the patient.

2. The method of claim 1 , comprising applying sufficient functional electrical stimulation to one or more of the gluteus medius, biceps femoris or gastrocnemius to achieve a leg abduction angle of from 30° to 45°.

3. The method of claim 1 , wherein the functional electrical stimulation is applied to the gluteus medius.

4. The method of claim 1 , wherein the functional electrical stimulation is applied to the biceps femoris.

5. The method of claim 4 , wherein the functional electrical stimulation is applied to the long head of the biceps femoris.

6. The method of claim 1 , wherein the functional electrical stimulation is applied to the gastrocnemius.

7. The method of claim 6 , wherein the functional electrical stimulation is applied to the lateral gastrocnemius.

8. The method of claim 1 , wherein the patient is human.

9. The method of claim 1 , wherein the patient suffers from osteoarthritis in the knee.

10. A method of treating or preventing osteoarthritis of the knee joint in a patient in need thereof, the method comprising the following steps during gait:

a) applying functional electrical stimulation to one or more of the gluteus medius, biceps femoris or gastrocnemius of the leg in need of treatment prior to foot strike of the foot of the leg in need of treatment;

b) maintaining functional electrical stimulation to the muscle(s) stimulated in step a) for the period of stance of the leg in need of treatment;

c) ceasing functional electrical stimulation of the muscle stimulated in step a) at the end of the period of stance of the leg in need of treatment;

d) optionally repeating steps a) to c) in respect of the corresponding muscle(s) of the patient's other leg; and

e) repeating steps a) to d) for each stride of the patient.

11. The method of claim 10 , comprising applying sufficient functional electrical stimulation to one or more of the gluteus medius, biceps femoris or gastrocnemius of up to 150 mA, preferably from 5 to 80 mA.

12. The method of claim 10 , wherein the functional electrical stimulation is applied to the gluteus medius.

13. The method of claim 10 , wherein the functional electrical stimulation is applied to the biceps femoris.

14. The method of claim 13 , wherein the functional electrical stimulation is applied to the long head of the biceps femoris.

15. The method of claim 10 , wherein the functional electrical stimulation is applied to the gastrocnemius.

16. The method of claim 15 , wherein the functional electrical stimulation is applied to the lateral gastrocnemius.

17. The method of claim 1 , wherein the patient is human.

18. A method of treating knee instability during gait in a patient with an anterior cruciate ligament deficiency, the method comprising the following steps during gait:

a) applying functional electrical stimulation to the biceps femoris of the leg having an anterior cruciate ligament deficiency, prior to foot strike of the foot of said leg;

b) maintaining functional electrical stimulation to the biceps femoris for the stance period of said leg;

c) ceasing functional electrical stimulation of the biceps femoris at the end of the stance period of said leg;

d) optionally repeating steps a) to c) in respect of the patient's other leg; and

e) repeating steps a) to d) for each stride of the patient.

19. The method of claim 18 , wherein the patient is human.

Assignments (3)
CHANGE OF NAME Recorded Jan 22, 2020
From: IMPERIAL WHITE CITY INCUBATOR LIMITED
To: IMPERIAL COLLEGE INNOVATIONS LIMITED
Reel/Frame 051586/0673 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 22, 2020
From: IMPERIAL INNOVATIONS LIMITED
To: IMPERIAL WHITE CITY INCUBATOR LIMITED
Reel/Frame 052178/0172 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 13, 2018
From: BILL, ANTHONY MJ; RANE, LANCE
To: IMPERIAL INNOVATIONS LIMITED
Reel/Frame 045537/0361 →
Continuity (2)
Provisional Application 62453395 · Feb 1, 2017
Related Publication 20180221658A1 · Aug 9, 2018