Optimizing mifepristone levels for Cushing's patients

1. A method for improving efficacy of mifepristone treatment in a patient suffering from Cushing's syndrome, the method comprising:

treating the patient with seven or more daily doses of mifepristone over a period of seven or more days;

testing the serum levels of the patient to determine whether the blood levels of mifepristone are greater than 1631 ng/mL; and

adjusting the daily dose of the patient to achieve mifepristone blood levels greater than 1631 ng/mL,

with the proviso that the patient is not already suffering from a condition indicated for treatment with mifepristone, thereby improving the efficacy of mifepristone treatment for the patient suffering from Cushing's syndrome.

2. The method of claim 1 , wherein each of the seven or more daily doses of mifepristone are administered orally.

3. The method of claim 1 , wherein the daily dose is at least 300 mg.

4. The method of claim 1 , wherein the daily dose is at least 600 mg.

5. The method of claim 1 , wherein the daily dose is at least 900 mg.

6. The method of claim 1 , wherein the daily dose is at least 1200 mg.

7. The method of claim 1 , wherein the patient is treated with 28 or more daily doses over a period of 28 or more days.

8. The method of claim 1 , wherein the testing is performed by a plasma sampling collection device suitable for detecting mifepristone serum levels.

9. The method of claim 1 , wherein the adjusting step comprises increasing the daily dose of the patient to achieve mifepristone blood levels greater than 1631 ng/mL.