IP Library › Granted Patent US 10,322,117
Granted Patent B2
US 10,322,117 · App. 15/919,923 · Granted Jun 18, 2019

Compositions for the treatment of hypertension

Inventors: Anthony Rodgers (Sydney, AU); Stephen MacMahon (Sydney, AU)
Assignee: THE GEORGE INSTITUTE FOR GLOBAL HEALTH
A61K31/4422A61K31/404A61K31/41A61K31/4184A61K31/4418A61K31/549A61P9/12
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Quick Facts
Patent No.
US 10,322,117
App. No.
15/919,923
Filed
Mar 13, 2018
Granted
Jun 18, 2019
Kind
B2
Art Unit
1627
USPC
514/356
Abstract

Provided herein are pharmaceutical compositions that are useful for the treatment of hypertension comprising an angiotensin II receptor blocker, a diuretic, and a calcium channel blocker.

Claims (12)

1. A pharmaceutical composition comprising:

(a) telmisartan;

(b) indapamide; and

(c) amlodipine besylate;

wherein the dose of telmisartan is from about 8 mg to about 12 mg, the dose of indapamide is from about 0.5 mg to about 0.75 mg, and the dose of amlodipine besylate is from about 1 mg to about 1.5 mg; and wherein the pharmaceutical composition is free of beta-blocker.

2. The pharmaceutical composition of claim 1 , wherein the dose of indapamide is about 0.625 mg.

3. The pharmaceutical composition of claim 1 , wherein the dose of amlodipine besylate is about 1.25 mg.

4. The pharmaceutical composition of claim 1 , wherein the dose of telmisartan is about 10 mg.

5. The pharmaceutical composition of claim 1 , wherein the dose of indapamide is about 0.625 mg and the dose of amlodipine besylate is about 1.25 mg.

6. The pharmaceutical composition of claim 1 , wherein the dose of indapamide is about 0.625 mg and the dose of telmisartan is about 10 mg.

7. The pharmaceutical composition of claim 1 , wherein the dose of amlodipine besylate is about 1.25 mg and the dose of telmisartan is about 10 mg.

8. The pharmaceutical composition of claim 1 , wherein the dose of indapamide is about 0.625 mg, the dose of amlodipine besylate is about 1.25 mg, and the dose of telmisartan is about 10 mg.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 28, 2018
From: RODGERS, ANTHONY; MACMAHON, STEPHEN
To: THE GEORGE INSTITUTE FOR GLOBAL HEALTH
Reel/Frame 046227/0475 →
Continuity (3)
Continuation PCTIB2018000083 · Jan 23, 2018
Provisional Application 62450324 · Jan 25, 2017
Related Publication 20180243278A1 · Aug 30, 2018
Cited By (5)
US 12,285,415 US 12,465,599 US 12,521,380 US 12,661,345 US 12,673,047