Modulators of Sestrin-GATOR2 interaction and uses thereof
The present invention provides compounds, compositions thereof, and methods of using the same.
1. A method of treating treatment-resistant depression in a patient in need thereof, said method comprising administering to said patient a compound of formula I-90 or pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable composition thereof:
2. The method according to claim 1 , wherein said method further comprises administering to said patient an additional therapeutic agent or therapy.
3. The method of claim 1 , wherein the pharmaceutically acceptable composition comprising a compound of formula I-90 further comprises a pharmaceutically acceptable carrier, adjuvant, or vehicle.
4. The method according to claim 3 , wherein said method further comprises administering to said patient an additional therapeutic agent or therapy.
5. The method according to claim 1 , wherein the treatment-resistant depression is resistant to first line treatments.
6. The method according to claim 1 , wherein the treatment-resistant depression is resistant to second line treatments.