IP Library › Granted Patent US 10,687,876
Granted Patent B2
US 10,687,876 · App. 15/970,204 · Granted Jun 23, 2020

Bone fusion system

Inventors: Frank D. Vrionis (Tampa, FL); Kamran Aghayev (Tampa, FL); Sabrina A Gonzalez Blohm (Tampa, FL); James J. Doulgeris (Oldsmar, FL)
Assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc.; University of South Florida
A61B17/861A61B17/70A61B17/863A61B17/8635A61B17/8665A61B17/8685A61F2/447A61F2/4455A61B17/8625A61F2002/2835A61F2002/3027A61F2002/3055A61F2002/30153A61F2002/30354A61F2002/30405A61F2002/30471A61F2002/30479A61F2002/30492A61F2002/30505A61F2002/30556A61F2002/30565A61F2002/30579A61F2002/30772A61F2002/30904A61F2002/4475
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Quick Facts
Patent No.
US 10,687,876
App. No.
15/970,204
Granted
Jun 23, 2020
Kind
B2
Abstract

A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed. The screws include a threaded tip connected to a main shaft and a threaded outer sleeve that rotates relative to the outer shaft until locked down. Independent rotation of the threaded outer sleeve relative to the threaded distal tip allows compression or distraction to modify the gap between the vertebral bodies. The screws are passed from the inferior to superior vertebra or superior to inferior, for example, through a trans-pedicular route to avoid neurological compromise. At the same time, the path of screw insertion is oriented to reach superior or inferior vertebra. An intervertebral cage of the system is configured for lateral expansion from a nearly straight configuration to form a large footprint in the disc space. The screws and cage may be combined for improved fixation with minimal invasiveness.

Claims (111)

1. An intervertebral cage, comprising:

a) a first longitudinal bar pair and a second longitudinal bar pair, each longitudinal bar pair comprising an upper bar and a lower bar, wherein a longitudinal bar pairs are spaced from each other on opposite sides of a midline vertical plane of the cage;

b) at least two spacers connected by a threaded rod and each moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane; and

c) at least one separator movable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between at least a portion of the bars of that longitudinal bar pair.

2. The cage of claim 1 , wherein movement of the at least two spacers within the space between the longitudinal bar pairs causes movement of the longitudinal bar pairs away from each other in a horizontal direction substantially perpendicular to the vertical plane of the cage.

3. The cage of claim 1 , wherein movement of the separator between the upper and lower bars of the longitudinal bar pair causes vertical separation of the bars of that pair in a direction substantially parallel to the longitudinal plane of the cage.

4. The cage of claim 1 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, and wherein each separator has a height dimension that defines an extent of separation between the bars of a given longitudinal bar pair caused by the separator.

5. The cage of claim 1 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, wherein one or more bar separators have different height dimensions, and wherein movement of the plurality of separators having different height dimensions between the longitudinal bar pairs results in asymmetric vertical expansion of the cage.

6. The cage of claim 1 , wherein in the threaded rod extends along the vertical midline plane of the cage, and actuation of the threaded rod causes movement of both spacers of the at least two spacers towards each other within the space between the longitudinal bar pairs.

7. The cage of claim 1 , wherein:

(a) the at least two spacers comprises a first spacer positioned in proximity to first ends of the longitudinal bars;

(b) the at least one separator comprises a first separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a second separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a first connector pivotably connected to the first spacer and to the first separator; and

(e) a second connector pivotably connected to the first spacer and to the second separator;

(f) wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

8. The cage of claim 7 , wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs prior to movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs, which causes vertical separation between the longitudinal bars.

9. The cage of claim 7 , wherein:

(a) the at least two spacers further comprises a second spacer positioned in proximity to second ends of the longitudinal bars;

(b) the at least one separator further comprises a third separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a fourth separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a third connector pivotably connected to the second spacer and to the third separator; and

(e) a fourth connector pivotably connected to the second spacer and the to the fourth separator;

(f) wherein movement of the second spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the third and fourth separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

10. The cage of claim 1 , wherein the at least two spacers includes a cam surface configured to interact with surfaces of the longitudinal bar pairs.

11. The cage of claim 10 , further comprising a connector pivotably connecting the at least two spacers with the at least one separator.

12. The cage of claim 1 , wherein the at least one separator includes at least one sloped front surface configured to cause separation between the portion of the bars.

13. An intervertebral cage, comprising:

a) a first longitudinal bar pair and a second longitudinal bar pair, each longitudinal bar pair comprising an upper bar and a lower bar, wherein the longitudinal bar pairs are spaced from each other on opposite sides of a midline vertical plane of the cage;

b) at least one spacer moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane, wherein the at least one spacer comprises a first spacer positioned in proximity to first ends of the longitudinal bars; and

c) at least one separator movable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between at least a portion of the bars of that longitudinal bar pair, wherein the at least one separator comprises a first separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair and a second separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair,

(d) a first connector pivotably connected to the first spacer and to the first separator; and

(e) a second connector pivotably connected to the first spacer and to the second separator;

(f) wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

14. The cage of claim 13 , wherein movement of the at least one spacer within the space between the longitudinal bar pairs causes movement of the longitudinal bar pairs away from each other in a horizontal direction substantially perpendicular to the vertical plane of the cage.

15. The cage of claim 13 , wherein movement of the separator between the upper and lower bars of the longitudinal bar pair causes vertical separation of the bars of that pair in a direction substantially parallel to the longitudinal plane of the cage.

16. The cage of claim 13 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, and wherein each separator has a height dimension that defines an extent of separation between the bars of a given longitudinal bar pair caused by the separator.

17. The cage of claim 13 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, wherein one or more separators have different height dimensions, and wherein movement of the plurality of separators having different height dimensions between the longitudinal bar pairs results in asymmetric vertical expansion of the cage.

18. The cage of claim 13 , further comprising two spacers each moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane, wherein the two spacers are connected by a threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

19. The cage of claim 13 , wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs prior to movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs, which causes vertical separation between the longitudinal bars.

20. The cage of claim 13 , wherein:

(a) the at least one spacer further comprises a second spacer positioned in proximity to second ends of the longitudinal bars;

(b) the at least one separator further comprises a third separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a fourth separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a third connector pivotably connected to the second spacer and to the third separator; and

(e) a fourth connector pivotably connected to the second spacer and the to the fourth separator;

(f) wherein movement of the second spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the third and fourth separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

21. The cage of claim 20 , further comprising a threaded rod, wherein the two spacers are connected by the threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

22. The cage of claim 13 , wherein the at least one spacer includes a cam surface configured to interact with surfaces of the longitudinal bar pairs.

23. The cage of claim 22 , further comprising a connector pivotably connecting the at least one spacer with the at least one separator.

24. The cage of claim 13 , wherein the at least one separator includes at least one sloped front surface configured to cause separation between the portion of the bars.

25. An intervertebral cage, comprising:

a) a first longitudinal bar pair and a second longitudinal bar pair, each longitudinal bar pair comprising an upper bar and a lower bar, wherein the longitudinal bar pairs are spaced from each other on opposite sides of a midline vertical plane of the cage;

b) at least one spacer moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane, wherein the at least one spacer includes a cam surface configured to interact with surfaces of the longitudinal bar pairs; and

c) at least one separator movable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between at least a portion of the bars of that longitudinal bar pair.

26. The cage of claim 25 , wherein movement of the at least one spacer within the space between the longitudinal bar pairs causes movement of the longitudinal bar pairs away from each other in a horizontal direction substantially perpendicular to the vertical plane of the cage.

27. The cage of claim 25 , wherein movement of the separator between the upper and lower bars of the longitudinal bar pair causes vertical separation of the bars of that pair in a direction substantially parallel to a longitudinal plane of the cage.

28. The cage of claim 25 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, and wherein each separator has a height dimension that defines an extent of separation between the bars of a given longitudinal bar pair caused by the separator.

29. The cage of claim 25 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, wherein one or more bar separators have different height dimensions, and wherein movement of the plurality of separators having different height dimensions between the longitudinal bar pairs results in asymmetric vertical expansion of the cage.

30. The cage of claim 25 , further comprising two spacers each moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane, wherein the two spacers are connected by a threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

31. The cage of claim 25 , wherein:

(a) the at least one spacer comprises a first spacer positioned in proximity to first ends of the longitudinal bars;

(b) the at least one separator comprises a first separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a second separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a first connector pivotably connected to the first spacer and to the first separator; and

(e) a second connector pivotably connected to the first spacer and to the second separator;

(f) wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

32. The cage of claim 31 , wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs prior to movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs, which causes vertical separation between the longitudinal bars.

33. The cage of claim 31 , wherein:

(a) the at least one spacer further comprises a second spacer positioned in proximity to second ends of the longitudinal bars;

(b) the at least one separator further comprises a third separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a fourth separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a third connector pivotably connected to the second spacer and to the third separator; and

(e) a fourth connector pivotably connected to the second spacer and the to the fourth separator;

(f) wherein movement of the second spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the third and fourth separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

34. The cage of claim 33 , further comprising a threaded rod, wherein the two spacers are connected by the threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

35. The cage of claim 25 , further comprising a connector pivotably connecting the at least one spacer with the at least one separator.

36. An intervertebral cage, comprising:

a) a first longitudinal bar pair and a second longitudinal bar pair, each longitudinal bar pair comprising an upper bar and a lower bar, wherein the longitudinal bar pairs are spaced from each other on opposite sides of a midline vertical plane of the cage;

b) at least one spacer moveable within the space between the longitudinal bar pairs to cause movement of at least a portion of the longitudinal bar pairs away from each other and from the midline vertical plane; and

c) at least one separator movable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between at least a portion of the bars of that longitudinal bar pair, wherein the at least one separator includes at least one sloped front surface configured to cause separation between the portion of the bars.

37. The cage of claim 36 , wherein movement of the at least one spacer within the space between the longitudinal bar pairs causes movement of the longitudinal bar pairs away from each other in a horizontal direction substantially perpendicular to the vertical plane of the cage.

38. The cage of claim 36 , wherein movement of the separator between the upper and lower bars of the longitudinal bar pair causes vertical separation of the bars of that pair in a direction substantially parallel to the longitudinal plane of the cage.

39. The cage of claim 36 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, and wherein each separator has a height dimension that defines an extent of separation between the bars of a given longitudinal bar pair caused by the separator.

40. The cage of claim 36 , further comprising a plurality of separators, wherein each separator is moveable between the upper and lower bars of one of the longitudinal bar pairs to cause separation between the bars of the longitudinal bar pair which it moves between, wherein one or more bar separators have different height dimensions, and wherein movement of the plurality of separators having different height dimensions between the longitudinal bar pairs results in asymmetric vertical expansion of the cage.

41. The cage of claim 36 , wherein the at least one spacer is a first and second spacer, and further comprising a threaded rod, wherein the two spacers are connected by the threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

42. The cage of claim 36 , wherein:

(a) the at least one spacer comprises a first spacer positioned in proximity to first ends of the longitudinal bars;

(b) the at least one separator comprises a first separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a second separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a first connector pivotably connected to the first spacer and to the first separator; and

(e) a second connector pivotably connected to the first spacer and to the second separator;

(f) wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

43. The cage of claim 42 , wherein movement of the first spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs prior to movement of the first and second separators between the longitudinal bars of the first and second longitudinal bar pairs, which causes vertical separation between the longitudinal bars.

44. The cage of claim 42 , wherein:

(a) the at least one spacer further comprises a second spacer positioned in proximity to second ends of the longitudinal bars;

(b) the at least one separator further comprises a third separator positioned to be moved between the upper and lower bars of the first longitudinal bar pair to cause separation between at least a portion of the bars of said first longitudinal bar pair;

(c) the at least one separator further comprises a fourth separator positioned to be moved between the upper and lower bars of the second longitudinal bar pair to cause separation between at least a portion of the bars of said second longitudinal bar pair, and wherein the cage further comprises;

(d) a third connector pivotably connected to the second spacer and to the third separator; and

(e) a fourth connector pivotably connected to the second spacer and the to the fourth separator;

(f) wherein movement of the second spacer into the space between the longitudinal bar pairs causes horizontal separation of the longitudinal bar pairs; and

(g) wherein movement of the third and fourth separators between the longitudinal bars of the first and second longitudinal bar pairs causes vertical separation between the longitudinal bars.

45. The cage of claim 44 , further comprising a threaded rod, wherein the two spacers are connected by the threaded rod extending along the vertical midline plane of the cage, wherein actuation of the threaded rod causes movement of both spacers towards each other within the space between the longitudinal bar pairs.

46. The cage of claim 36 , wherein the at least one spacer includes a cam surface configured to interact with surfaces of the longitudinal bar pairs, and further comprising a connector pivotably connecting the at least one spacer with the at least one separator.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2018
From: AGHAYEV, KAMRAN
To: UNIVERSITY OF SOUTH FLORIDA
Reel/Frame 046822/0873 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2018
From: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
To: DOULGERIS, JAMES J
Reel/Frame 046822/0929 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2018
From: VRIONIS, FRANK D.; GONZALEZ BLOHM, SABRINA A.; DOULGERIS, JAMES J.
To: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
Reel/Frame 046822/0947 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 14, 2018
From: DOULGERIS, JAMES J
To: UNIVERSITY OF SOUTH FLORIDA
Reel/Frame 046822/0972 →
Continuity (4)
Continuation 15718786 · Sep 28, 2017
Continuation 14347442
Provisional Application 61543482 · Oct 5, 2011
Related Publication 20180250050A1 · Sep 6, 2018
Cited By (8)
US 12,279,969 US 12,318,311 US 12,329,652 US 12,390,344 US 12,414,858 US 12,533,240 US 12,551,254 US 12,714,572