IP Library Granted Patent US 10,818,379
Granted Patent B2
US 10,818,379 · App. 15/974,591 · Granted Oct 27, 2020

Methods and systems for analyte information processing

Inventors: Rajaram Krishnan (San Diego, CA); Iryna Clark (Del Mar, CA); Robert Turner (San Diego, CA); Robert Kovelman (La Jolla, CA); Juan Pablo Hinestrosa Salazar (San Diego, CA); David Liu (San Diego, CA)
Assignee: BIOLOGICAL DYNAMICS, INC.
G16H10/40B01L3/502715G01N27/44791G01N33/53G16H10/20G16H30/20B01L3/5027B01L2300/023B01L2400/0424
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Quick Facts
Patent No.
US 10,818,379
App. No.
15/974,591
Granted
Oct 27, 2020
Kind
B2
Abstract

Systems, devices, media, methods, and kits are disclosed to integrate and exchange information of analyte analysis kits. Analyte analysis can be performed and presented using in association with advertising or questions.

Claims (43)

1. A computer-implemented system for performing a biological assay, comprising:

a) a mobile computing device comprising: at least one processor, a memory, a display, a camera, and an operating system configured to perform executable instructions;

b) an analyte analysis apparatus configured to reversibly accept and position the mobile computing device and an analyte analysis cartridge such that the camera of the mobile computing device is positioned to capture an image of a result field of the analyte analysis cartridge, said analyte analysis cartridge being configured to receive and process a biological material of an individual; and

c) a computer program stored in the memory of the mobile computing device, the computer program including instructions executable by the at least one processor to create an application comprising:

i) a software module controlling the analyte analysis apparatus to carry out the biological assay by performing analyte testing of the biological material using the analyte analysis cartridge, wherein said analyte testing generates an optical signal based on an analyte in the biological sample, and controlling the camera to capture the image of the optical signal in the result field;

ii) a software module performing data analysis on the image to generate a result, wherein the data analysis comprises performing image processing on pixel image data;

iii) a software module presenting the result on the display of the mobile computing device; and

iv) a software module selecting one or more ads from a population of ads or one or more questions from a population of questions to present during at least one of the analyte testing or the data analysis before presenting the result, wherein the result is locked until the one or more ads have been presented or the one or more questions have been answered, wherein the one or more ads or one or more questions are targeted to the individual based on at least the biological assay and optionally in combination with one or more of a user profile of the individual, the analyte, a prior analyte testing result, or a location of the mobile computing device.

2. The system of claim 1 , wherein the analyte analysis cartridge is a dielectrophoresis (DEP) cartridge.

3. The system of claim 1 , wherein a response by the individual to the one or more ads or the one or more questions is added to the user profile of the individual.

4. The system of claim 1 , wherein the software module selecting the one or more ads or the one or more questions receives instructions from a remote server for selection of the one or more ads from the population of ads or the one or more questions from the population of questions, wherein the selection is based on analysis performed by the remote server.

5. The system of claim 1 , wherein the one or more ads or the one or more questions are provided by a third-party ad network.

6. The system of claim 1 , wherein the application further comprises a software module providing an interface allowing upload of the result to an online database.

7. The system of claim 1 , wherein the application further comprises a software module providing a query interface allowing search of an online database.

8. The system of claim 1 , wherein the application further comprises a software module providing at least one of a treatment recommendation and a healthcare provider recommendation generated by a machine learning algorithm based on the user profile of the individual, the analyte, the result, the location of the mobile computing device, historical treatment outcome data for a cohort of patients matched to the individual, healthcare provider information, or a combination thereof.

9. The system of claim 1 , wherein the result is geo-tagged with the location of the mobile computing device and uploaded to a database.

10. A computer-implemented method for performing a biological assay, comprising:

a) communicating, by a mobile computing device, with an analyte analysis apparatus configured to reversibly accept and position the mobile computing device and an analyte analysis cartridge such that a camera of the mobile computing device is positioned to capture an image of a result field of the analyte analysis cartridge, said analyte analysis cartridge being configured to receive and process a biological material of an individual;

b) transmitting, by the mobile computing device, a control signal to the analyte analysis apparatus to carry out the biological assay by performing analyte testing of the biological material of the individual using the analyte analysis cartridge, wherein said analyte testing generates an optical signal based on an analyte in the biological sample, and controlling the camera of the mobile computing device to capture the image of the optical signal in the result field;

c) performing data analysis on the image to generate a result, wherein the data analysis comprises performing image processing on pixel image data;

d) presenting, by the mobile computing device, the result on a display; and

e) selecting, by the mobile computing device, one or more ads from a population of ads or one or more questions from a population of questions to present during at least one of the analyte testing or the data analysis before presenting the result, wherein the result is locked until the one or more ads have been presented or the one or more questions have been answered, wherein the one or more ads or one or more questions are targeted to the individual based on at least the biological assay and optionally in combination with one or more of a user profile of the individual, the analyte, a prior analyte testing result, or a location of the mobile computing device.

11. The method of claim 10 , wherein the mobile computing device or the analyte analysis apparatus provides power to the analyte analysis cartridge.

12. The method of claim 11 , wherein the analyte analysis cartridge is a dielectrophoresis (DEP) cartridge.

13. The method of claim 10 , wherein the mobile computing device receives instructions from a remote server for selection of the one or more ads from the population of ads or the one or more questions from the population of questions, wherein the selection is based on analysis performed by the remote server.

14. The method of claim 10 , further comprising providing at least one of a treatment recommendation and a healthcare provider recommendation generated by a machine learning algorithm based on the user profile of the individual, the analyte, the result, the location of the mobile computing device, historical treatment outcome data for a cohort of patients matched to the individual, healthcare provider information, or a combination thereof.

15. The method of claim 10 , wherein the result is geo-tagged with the location of the mobile computing device and uploaded to a database.

16. Non-transitory computer readable storage media encoded with a program including instructions executable by at least one processor of a mobile computing device to create an application for performing a biological assay, said application comprising:

a) a software module communicating with an analyte analysis apparatus configured to reversibly accept and position the mobile computing device and an analyte analysis cartridge such that a camera of the mobile computing device is positioned to capture an image of a result field of the analyte analysis cartridge, said analyte analysis cartridge being configured to receive and process a biological material of an individual;

b) a software module transmitting a control signal to an analyte analysis apparatus to carry out the biological assay by performing analyte testing of the biological material of the individual using the analyte analysis cartridge, wherein said analyte testing generates an optical signal based on an analyte in the biological sample, and controlling the camera to capture the image of the optical signal in the result field of the analyte analysis cartridge;

c) a software module performing data analysis on the image to generate a result, wherein the data analysis comprises performing image processing on pixel image data;

d) a software module presenting the result on a display of the mobile computing device; and

e) a software module selecting one or more ads from a population of ads or one or more questions from a population of questions to present during at least one of the analyte testing or the data analysis before presenting the result, wherein the result is locked until the one or more ads have been presented or the one or more questions have been answered, wherein the one or more ads or one or more questions are targeted to the individual based on at least the biological assay and optionally in combination with one or more of a user profile of the individual, the analyte, a prior analyte testing result, or a location of the mobile computing device.

17. The media of claim 16 , wherein the application further comprises a software module providing at least one of a treatment recommendation and a healthcare provider recommendation generated by a machine learning algorithm based on the user profile of the individual, the analyte, the result, the location of the mobile computing device, historical treatment outcome data for a cohort of patients matched to the individual, healthcare provider information, or a combination thereof.

18. The media of claim 16 , wherein the result is geo-tagged with the location of the mobile computing device.

19. A computer-implemented system for performing a biological assay, comprising:

a) a mobile computing device comprising: at least one processor, a memory, a display, a camera, and an operating system configured to perform executable instructions;

b) an analyte analysis apparatus configured to reversibly accept and position the mobile computing device and an analyte analysis cartridge such that the camera of the mobile computing device is positioned to capture an image of a result field of the analyte analysis cartridge, said analyte analysis cartridge being configured to receive and process a biological material of an individual; and

c) a computer program stored in the memory of the mobile computing device, the computer program including instructions executable by the at least one processor to create an application comprising:

i) a software module controlling the analyte analysis apparatus to carry out the biological assay by performing analyte testing of the biological material using the analyte analysis cartridge, wherein said analyte testing generates an optical signal based on an analyte in the biological sample, and controlling the camera to capture the image of the optical signal in the result field;

ii) a software module performing data analysis on the image to generate a result, wherein the data analysis comprises performing image processing on pixel image data;

iii) a software module presenting the result on the display of the mobile computing device; and

iv) a software module selecting one or more ads from a population of ads or one or more questions from a population of questions to present during at least one of the analyte testing or the data analysis before presenting the result, wherein the result is locked until the one or more ads have been presented or the one or more questions have been answered, wherein the one or more ads or one or more questions are targeted to the individual based on user information comprising a user profile of the individual, the analyte, a prior analyte testing result, a location of the mobile computing device, or a combination thereof, wherein the user information is updated based on at least the result of the analyte testing.

Assignments (3)
SECURITY INTEREST Recorded Jun 12, 2024
From: BIOLOGICAL DYNAMICS, INC.
To: THE JACOBS FAMILY TRUST DATED JUNE 2, 1980, SEPARATE PROPERTY OF IRWIN MARK JACOBS
Reel/Frame 067712/0940 →
SECURITY INTEREST Recorded Mar 2, 2023
From: BIOLOGICAL DYNAMICS, INC.
To: PARIAN ZEUS LP, IN ITS CAPACITY AS COLLATERAL AGENT ON BEHALF OF THE SECURED PARTIES
Reel/Frame 062917/0195 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 13, 2018
From: KRISHNAN, RAJARAM; CLARK, IRYNA; TURNER, ROBERT; KOVELMAN, ROBERT; HINESTROSA SALAZAR, JUAN PABLO; LIU, DAVID
To: BIOLOGICAL DYNAMICS, INC.
Reel/Frame 047512/0391 →
Continuity (2)
Provisional Application 62503174 · May 8, 2017
Related Publication 20180322941A1 · Nov 8, 2018
Cited By (6)
US 12,233,412 US 12,275,010 US 12,505,711 US 12,574,294 US 12,629,696 US 12,664,841