IP Library Granted Patent US 10,420,346
Granted Patent B2
US 10,420,346 · App. 16/011,154 · Granted Sep 24, 2019

Silver nanoparticle-enhanced photosensitizers

Inventors: Peng Zhang (Cincinnati, OH); Niranga Wijesiri (Cincinnati, OH); Hong Tang (Cincinnati, OH)
Assignee: University Of Cincinnati
A01N59/16A01N25/28A01N43/34A61K41/0057A61K41/0071A61K47/6923C01G5/006C07D487/22A01N25/26B82Y5/00C01P2002/01C01P2004/64
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Quick Facts
Patent No.
US 10,420,346
App. No.
16/011,154
Granted
Sep 24, 2019
Kind
B2
Abstract

The present invention relates generally to compositions and methods of killing fungi using a surface plasmon coupled to a photosensitizer. A nanostructure ( 10 ) may include a silver nanoparticle core ( 12 ), a mesoporous silica shell ( 14 ), and a photosensitizer ( 16 ). A method of killing fungi may include contacting fungi with a nanostructure ( 10 ) including a silver nanoparticle core ( 12 ), a mesoporous silica shell ( 14 ), and a photosensitizer ( 16 ) to form a blend and exposing the blend to light.

Claims (7)

1. A method of killing fungi comprising:

contacting fungi with a nanostructure comprising a silver nanoparticle core, a mesoporous silica shell, and a photosensitizer to form a blend; and

exposing said blend to light.

2. The method claimed in claim 1 , wherein said fungi is Tricophyton rubrum.

3. The method claimed in claim 1 , wherein the light is produced by a light emitting diode.

4. The method claimed in claim 1 , wherein said light has a broad spectrum, the broad spectrum including visible and near infrared wavelengths.

5. The method of claim 1 , wherein said blend comprises a Ag@mSiO2@HPIX hybrid.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 12, 2022
From: UNIVERSITY OF CINCINNATI
To: THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY
Reel/Frame 058717/0153 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 29, 2018
From: ZHANG, PENG; WIJESIRI, NIRANGA; TANG, HONG
To: UNIVERSITY OF CINCINNATI
Reel/Frame 046236/0134 →
Continuity (3)
Continuation In Part 15123549
Provisional Application 61949509 · Mar 7, 2014
Related Publication 20180295840A1 · Oct 18, 2018