Autoinjector apparatus

1. A single-use cassette for use with an autoinjector, the cassette comprising:

a housing;

an inner sleeve disposed in the housing and movable between first and second positions along a longitudinal axis, the inner sleeve comprising one or more side walls defining an interior, and at least one receptacle having a rearward opening, the at least one receptacle separate from and disposed adjacent to the interior;

a syringe disposed in the interior of the inner sleeve; and

lock cap for securing the syringe in the inner sleeve, the lock cap including an elastomeric bumper, the lock cap affixed to a distal end of the inner sleeve with the elastomeric bumper contacting a distal end of the syringe, wherein the lock cap comprises at least one arm member extending generally parallel to the longitudinal axis for inserting into the at least one receptacle.

2. The cassette of claim 1 , wherein the at least one arm member of the lock cap comprises a barb arrangement for gripping an inner surface of the receptacle of the inner sleeve.

3. The cassette of claim 1 , wherein the cassette further comprises a shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing.

4. The cassette of claim 3 , wherein the shield remover comprises an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette.

5. The cassette of claim 1 , further comprising a therapeutic product in the syringe.

6. The cassette of claim 5 , wherein the therapeutic product is Epogen®, Aranesp®, Enbrel® Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva®, Prolia®, an antibody to IL-17 Receptor A, antagonist of angiopoietin-2, a TNF blocker or inhibitor, etanercept, adalimumab, certolizumab, golimumab or infliximab.

7. The cassette of claim 1 , further comprising a cassette identification arrangement on a surface of the housing to enable the auto injector to identify the cassette.

8. The cassette of claim 7 , wherein the cassette identification arrangement comprises at least one projection.

9. An apparatus for injection of a therapeutic product, the apparatus comprising:

an auto injector; and

a single-use cassette for use with the injector, the cassette comprising:

a housing;

an inner sleeve disposed in the housing and movable between first and second positions along a longitudinal axis, the inner sleeve comprising one or more sidewalls defining an interior, and at least one receptacle having a rearward opening, the at least one receptacle separate from and disposed adjacent to the interior;

a syringe disposed in the inner sleeve; and

a lock cap for securing the syringe in the inner sleeve, the lock cap including an elastomeric bumper, the lock cap affixed to a distal end of the inner sleeve with the elastomeric bumper contacting a distal end of the syringe, wherein the lock cap comprises at least one arm member extending generally parallel to the longitudinal axis and inserted into the at least one receptacle.

10. The apparatus of claim 9 , wherein the at least one arm member of the lock cap comprises a barb arrangement for gripping an inner surface of the receptacle of the inner sleeve.

11. The apparatus of claim 9 , wherein the cassette further comprises a shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette.

12. The apparatus of claim 11 , wherein the autoinjector comprises a pin for pushing the tab out of the aperture defined in the wall of the housing when the cassette is placed in the injector to thereby allow the shield remover to be removed from the cassette.

13. The apparatus of claim 11 , wherein the shield remover comprises an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette.

14. The apparatus of claim 9 , further comprising a therapeutic product in the syringe.

15. The apparatus of claim 14 , wherein the therapeutic product is Epogen®, Aranesp®, Enbrel® Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva®, Prolia®, an antibody to IL-17 Receptor A, an antagonist to angiopoietin-2, a TNF blocker or inhibitor, etanercept, adalimumab, certolizumab, golimumab, or infliximab.

16. The apparatus of claim 9 , further comprising a cassette identification arrangement on a surface of the housing to enable the auto injector to identify the cassette.

17. The apparatus of claim 16 , wherein the cassette identification arrangement comprises at least one projection.

18. The apparatus of claim 16 , wherein the autoinjector comprises a detector for reading the cassette identification arrangement to identify the cassette.

19. The apparatus of claim 9 , wherein the at least one receptacle of the inner sleeve comprises at least two receptacles and the at least one arm member of the lock cap comprises at least two arm members inserted into the at least two receptacles.

20. A single-use cassette for use with an autoinjector, the cassette comprising:

a housing;

an inner sleeve disposed in the housing and movable between first and second positions along a longitudinal axis, the inner sleeve comprising one or more side walls defining an interior;

a syringe disposed in the interior of the inner sleeve; and

lock cap for securing the syringe in the inner sleeve, the lock cap including an elastomeric bumper, the lock cap affixed to a distal end of the inner sleeve with the elastomeric bumper contacting a distal end of the syringe, wherein the distal end of the inner sleeve comprises at least one receptacle adjacent to the interior of the inner sleeve having a rearward opening and the lock cap comprises at least one arm member extending generally parallel to the longitudinal axis for inserting into the at least one receptacle;

wherein the at least one receptacle of the inner sleeve comprises at least two receptacles and the at least one arm member of the lock cap comprises at least two arm members for inserting into the at least two receptacles.