Granted Patent
B2
US 10,280,182 · App. 16/046,382 · Granted May 7, 2019
Histone deacetylase inhibitors
Inventors:
Vincent Jacques (Somerville, MA); James R. Rusche (Framingham, MA); Norton P. Peet (North Andover, MA); Jasbir Singh (Naperville, IL)
Assignee:
BIOMARIN PHARMACEUTICAL INC.
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Abstract
This invention relates to generally inhibiting histone deacetylase (“HDAC”) enzymes (e.g., HDAC1, HDAC2, and HDAC3).
Claims (11)
1. A compound selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.
2. The compound or salt of claim 1 , having a structure:
3. The compound or salt of claim 1 , having a structure:
4. The compound or salt of claim 1 , having a structure:
5. The compound or salt of claim 1 , having a structure:
6. The compound or salt of claim 1 , having a structure:
7. The compound or salt of claim 1 , having a structure:
8. The compound or salt of claim 1 , having a structure:
9. The compound or salt of claim 1 , having a structure:
10. The compound or salt of claim 1 , having a structure:
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 14, 2018
From: JACQUES, VINCENT; RUSCHE, JAMES R.; PEET, NORTON P.; SINGH, JASBIR
To: REPLIGEN CORPORATION
Reel/Frame 046785/0617 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 14, 2018
From: REPLIGEN CORPORATION
To: BIOMARIN PHARMACEUTICAL INC.
Reel/Frame 046785/0745 →
Continuity (4)
Division
13823708
Provisional Application
61447416
· Feb 28, 2011