IP Library Granted Patent US 10,857,275
Granted Patent B2
US 10,857,275 · App. 16/060,487 · Granted Dec 8, 2020

Rotary blood pump for regulating a hemodynamic parameter successively to different target values

Inventor: Marcus Granegger (Perchtoldsdorf, DE)
Assignee: BERLIN HEART GMBH
A61M1/1086A61M1/101A61M1/1031A61M1/122A61M2205/3303A61M2205/3334A61M2205/50A61M2230/06A61M2230/30
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Quick Facts
Patent No.
US 10,857,275
App. No.
16/060,487
Granted
Dec 8, 2020
Kind
B2
Abstract

A blood pump for supporting the heart may be provided that includes: a rotor with delivery elements; a rotor drive; a pressure sensor; and a regulating device that regulates a pressure or a hemodynamic parameter by means of control of the rotor drive. The pressure and/or the hemodynamic parameter may be determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the pump. The regulating device may be suitable for regulating a hemodynamic parameter successively, such as periodically, to different target values. Using such regulation, the blood pump may be operated in an optimized manner, and operation of the blood pump may be varied in a targeted and patient-protective manner in order to attain certain goals.

Claims (36)

1. A blood pump for supporting a heart, the blood pump comprising:

a rotor with delivery elements;

a rotor drive;

a pressure sensor or another hemodynamic sensor;

a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and

a detection device configured to detect (1) a change in the pressure per unit of time in a detection range of the pressure sensor or (2) a change in the another hemodynamic parameter per unit of time in a detection range of the another hemodynamic sensor, and the detection device further configured to determine a maximum and/or a minimum of this value in a heart cycle.

2. The blood pump according to claim 1 comprising a processing device configured to relate the determined maximum values in the changes in pressure to the adjusted target pressure parameters, in particular and to determine a quotient from the determined maximum values of the changes in pressure and the adjusted target pressure parameters.

3. The blood pump according to claim 2 , wherein the processing device is configured to determine the slope of a line that is provided by a linear relationship between the determined maximum values of the changes in pressure and the adjusted target pressure parameters.

4. The blood pump according to claim 2 , wherein the processing device is configured to determine a quotient from a difference of two or more maximum values of the changes in pressure and the target pressure parameters associated with these values.

5. The blood pump according to claim 2 , wherein the adjusted target pressure parameter is end-diastolic pressure.

6. The blood pump according to claim 1 , wherein an echocardiograph is provided for performing echocardiographic measurements and is triggered by or synchronized with changes in the control of the rotor drive.

7. The blood pump according to claim 1 , wherein the regulating device is configured to regulate to varying target values during operation of the rotor drive such that at least one prespecified feature of a temporal curve of the pressure, a flow, a motor current, or a bearing position is attained.

8. The blood pump according to claim 7 , wherein the regulating device is configured to regulate the rotor drive alternating periodically such that an opening of the aortic valve may be evidenced based on a detected signal curve and/or a hemodynamic variable or an operating parameter of the blood pump.

9. The blood pump according to claim 7 , wherein the regulating device has a first operating state that corresponds to a first operation of the blood pump and a second operating state that is configured to regulate the rotor drive for a time interval such that an opening of the aortic valve may be evidenced based on a detected signal curve and/or a hemodynamic variable or an operating parameter of the blood pump.

10. The blood pump according to claim 9 , wherein a switching device is provided that switches between the first operating state and the second operating state according to a prespecified time pattern.

11. The blood pump according to claim 1 , wherein the another hemodynamic parameter that is regulated by the regulating device is the pulsatility of a pressure difference along the blood pump or of a flow rate through the blood pump.

12. The blood pump according to claim 1 , wherein a pressure sensor, or a flow sensor is connected directly to the regulating device.

13. The blood pump according to claim 12 , wherein the pressure sensor is an absolute pressure sensor.

14. The blood pump according to claim 1 , wherein the pressure sensor device comprises two pressure sensors, of which a first is arranged in or on the blood pump and a second is arranged in a volume not connected directly to the blood pump.

15. The blood pump according to claim 1 , wherein the pressure sensor and/or the another hemodynamic sensor are configured to determine the pressure and/or the another hemodynamic parameter, and/or the regulating device is configured to determine the pressure and/or the another hemodynamic parameter from operating parameters of the blood pump.

16. The blood pump according to claim 1 , wherein the regulating device is embodied such that the pressure and/or the another hemodynamic parameter is determined by means of one or a plurality of hemodynamic sensors and/or from operating parameters of the blood pump.

17. The blood pump according to claim 1 , wherein the pressure parameter is a hemodynamic pressure parameter.

18. The blood pump according to claim 1 , wherein the regulating device is configured to use an end-diastolic pressure determined from a cyclic pressure curve in the detection range of the pressure sensor.

19. The blood pump according to claim 1 , wherein the regulating device is suitable for periodically regulating to different target values.

20. A blood pump for supporting a heart, the blood pump comprising:

a rotor with delivery elements;

a rotor drive;

a pressure sensor or another hemodynamic sensor;

a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and

wherein an echocardiograph for performing echocardiographic measurements is configured to be triggered by or synchronized with changes in the control of the rotor drive.

21. A blood pump for supporting a heart, the blood pump comprising:

a rotor with delivery elements;

a rotor drive;

a pressure sensor or another hemodynamic sensor;

a regulating device configured to regulate a pressure or another hemodynamic parameter by control of the rotor drive, wherein the regulating device is configured to regulate a specific pressure parameter or another specific hemodynamic parameter successively to different target values; and

wherein the regulating device is configured to regulate to varying target values during operation of the rotor drive such that at least one prespecified feature of a temporal curve of the pressure, a flow, a motor current, or a bearing position is attained.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2023
From: GRANEGGER, MARCUS
To: BERLIN HEART GMBH
Reel/Frame 064345/0427 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 11, 2018
From: GRANEGGER, MARCUS
To: BERLIN HEART GMBH
Reel/Frame 047740/0572 →
Priority Claims (1)
EP 15199776 · Dec 14, 2015 · regional
Continuity (1)
Related Publication 20180361043A1 · Dec 20, 2018
Cited By (21)
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