LACTOBACILLUS CASEI FOR TREATING OBESITY AND ASSOCIATED METABOLIC DISORDERS
The strain Lactobacillus casei AH077 (NCIMB12019) produces a polysaccharide and increases energy excretion. The strain acts to block fat absorption and is used in the prevention or treatment of obesity and obesity-related metabolic syndrome.
1 - 26 . (canceled)
27 . A strain of Lactobacillus casei AH077 deposited with the NCIMB under accession number 42019.
28 . The strain as claimed in claim 27 in the form of viable cells.
29 . The strain as claimed in claim 27 in the form of non-viable cells.
30 . A formulation which comprises a strain of Lactobacillus casei AH077 deposited with the NCIMB under accession number 42019.
31 . The formulation as claimed in claim 29 which further comprises a probiotic material.
32 . The formulation as claimed in claim 29 which further comprises a prebiotic material.
33 . The formulation as claimed in claim 29 further comprising an ingestible carrier.
34 . The formulation as claimed in claim 29 wherein the ingestible carrier comprises a pharmaceutically acceptable carrier chosen from a capsule, a tablet, or a powder.
35 . The formulation as claimed in claim 29 wherein the ingestible carrier comprises a food product chosen from acidified milk, yoghurt, frozen yoghurt, milk powder, milk concentrate, cheese spreads, dressings, or beverages.
36 . The formulation as claimed in claim 29 which further comprises at least one of a protein or a peptide rich in glutamine/glutamate, a lipid, a carbohydrate, a vitamin, a mineral, a trace element, or a combination thereof.
37 . The formulation as claimed in claim 29 wherein the strain is present in an amount of more than 10 6 cfu per gram of the formulation.
38 . The formulation as claimed in claim 29 which further comprises one or more of an adjuvant, a bacterial component, a drug entity, or a biological compound.
39 . A freeze dried composition comprising the strain of Lactobacillus casei AH077 of claim 27 .
40 . A foodstuff comprising the strain of Lactobacillus casei AH077 of claim 27 .
41 . A medicament comprising the strain of Lactobacillus casei AH077 of claim 27 .
42 . A capsule comprising the strain of Lactobacillus casei AH077 of claim 27 .
43 . A method for preventing or treating a health condition, comprising administering a composition comprising a strain of Lactobacillus casei AH077 deposited with the NCIMB under accession number 42019 to a subject in need thereof.
44 . The method of claim 43 , wherein the method blocks fat absorption by the patient.
45 . The method of claim 43 , wherein the health condition includes obesity, obesity-related metabolic syndrome, or both.
46 . The method of claim 43 , wherein the health condition is non-alcoholic fatty liver disease (NAFLD).