IP Library Granted Patent US 10,918,585
Granted Patent B2
US 10,918,585 · App. 16/061,008 · Granted Feb 16, 2021

Anti-aging agent and anti-aging composition for skin

Inventors: Yuko Nakagami (Fujisawa, JP); Shinji Yamaki (Kawasaki, JP); Ichiro Fujita (Kawasaki, JP); Tadashi Yoneda (Chiba, JP)
Assignee: SHOWA DENKO K.K.
A61K8/60A61K8/73A61K31/702A61K31/7016A61K31/7034A61P43/00A61Q19/08
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Quick Facts
Patent No.
US 10,918,585
App. No.
16/061,008
Granted
Feb 16, 2021
Kind
B2
Abstract

Provided is an anti-aging agent for skin which contains, as an active component, an inositol derivative in which a monosaccharide or an oligosaccharide is bonded to inositol, in which a total amount of the monosaccharide or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit.

Claims (11)

1. An anti-aging composition for skin comprising one or more inositol derivatives in which glucose or an oligosaccharide comprising glucose as a constituent unit is bonded to inositol, and a total amount of the glucose or the oligosaccharide bonded to one inositol molecule is 1 or greater in terms of monosaccharide unit,

wherein the one or more inositol derivatives comprises, as an active component, at least one inositol derivative in which glucose or an oligosaccharide comprising glucose as a constituent unit is bonded to inositol, and a total amount of the glucose or the oligosaccharide bonded to one inositol molecule is 2 or greater in terms of monosaccharide unit,

a proportion of the active component among all of said one or more inositol derivatives contained in the anti-aging composition being 79% by mass or greater.

2. The anti-aging composition for skin according to claim 1 , wherein the inositol is myo-inositol.

3. The anti-aging composition for skin according to claim 1 , further comprising a pharmaceutically acceptable carrier.

4. The anti-aging composition for skin according to claim 1 , wherein the proportion of the active component among all inositol derivatives contained in the anti-aging composition is 97% by mass or greater.

5. The anti-aging composition for skin according to claim 1 , wherein the proportion of the active component among all inositol derivatives contained in the anti-aging composition is 100% by mass.

6. The anti-aging composition for skin according to claim 1 , comprising an inositol derivative in which glucose or an oligosaccharide comprising glucose as a constituent unit is bonded to inositol and in which a total amount of the glucose or the oligosaccharide bonded to one inositol molecule in terms of monosaccharide unit is 4 or greater, and

wherein a proportion of the inositol derivative in which glucose or an oligosaccharide comprising glucose as a constituent unit is bonded to inositol and in which a total amount of the glucose or the oligosaccharide bonded to one inositol molecule in terms of monosaccharide unit is 4 or greater among all inositol derivatives contained in the anti-aging composition is 23% by mass to 87% by mass.

7. A method of promoting expression of collagen genes or elastin genes in human fibroblast, comprising administering an effective amount of the anti-aging composition according to claim 1 to a human subject.

8. A method of suppressing a decrease in collagen or elastin in the skin dermis due to aging, comprising administering an effective amount of the anti-aging composition according to claim 1 to a human subject.

Assignments (3)
CHANGE OF ADDRESS Recorded Feb 14, 2024
From: RESONAC CORPORATION
To: RESONAC CORPORATION
Reel/Frame 066599/0037 →
CHANGE OF NAME Recorded Jun 23, 2023
From: SHOWA DENKO K.K.
To: RESONAC CORPORATION
Reel/Frame 064082/0513 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2018
From: NAKAGAMI, YUKO; YAMAKI, SHINJI; FUJITA, ICHIRO; YONEDA, TADASHI
To: SHOWA DENKO K.K.
Reel/Frame 046042/0386 →