IP Library › Patent Application 16077994
Patent Application
App. No. 16/077,994

MEDICAL ANALYTICS SYSTEM

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Patent No.
US None
App. No.
16/077,994
Abstract

Systems and methods of a medical analytics system are described herein. The medical analytics system can include a machine learning model for processing patient tissue images for either training the machine learning model or for clinical use, such as providing information for assisting a clinician with at least diagnosing a disease or condition of a patient. Implementations of the medical analytics system can further include a user interface that is configured to allow a user to interact with a patient image for assisting with diagnosing at least a part of the tissue captured in the patient image.

Claims (56)

1 . A system, comprising:

at least one processor; and

at least one memory including program code which when executed by the at least one processor provides operations comprising:

projecting a three-dimensional image of a patient tissue into a plurality of two-dimensional grayscale images;

applying at least one transformation algorithm to a first set of two-dimensional grayscale images to generate a first set of transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images of the first set of transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images, a plurality of feature values comprising a feature vector;

projecting the three-dimensional image into a two-dimensional color image;

applying at least one color transformation algorithm to a first set of two-dimensional color images to generate a first set of color-transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional color image and to each color-transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to the at least one two-dimensional color image and to each of the transformed two-dimensional color images, a plurality of color feature values comprising the feature vector;

collecting patient information;

generating, based on the collected patient information, one or more patient values comprising the feature vector;

training a machine learning model based on the feature vector and an associated diagnosis of the patient tissue, the machine learning model comprising a classifier having a weighted value assigned to each of the plurality of feature values, the plurality of color feature values, and the patient value.

2 . The system of claim 1 , further comprising:

defining, based on the training, a bio-marker that identifies one or more of the color value, the patient value, and at least one of the plurality of feature values, the bio-marker being part of the trained classifier for determining a diagnosis of an undiagnosed tissue captured in an undiagnosed three-dimensional image.

3 . The system of claim 2 , wherein the diagnosis includes whether the undiagnosed tissue is malignant or benign.

4 . The system of claim 2 , wherein the undiagnosed tissue is lung tissue or breast tissue.

5 . The system of claim 1 , wherein the three-dimensional image includes a part of a captured three-dimensional image generated by a three-dimensional imaging system.

6 . The system of claim 1 , wherein the three-dimensional image is projected onto at least two different dimensional planes thereby generating at least two different two-dimensional grayscale images.

7 . A computer-implemented method, comprising:

projecting a three-dimensional image of a patient tissue into a plurality of two-dimensional grayscale images;

applying at least one transformation algorithm to a first set of two-dimensional grayscale images to generate a first set of transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images of the first set of transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images, a plurality of feature values comprising a feature vector;

projecting the three-dimensional image into a two-dimensional color image;

applying at least one color transformation algorithm to a first set of two-dimensional color images to generate a first set of color-transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional color image and to each color-transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to the at least one two-dimensional color image and to each of the transformed two-dimensional color images, a plurality of color feature values comprising the feature vector;

collecting patient information;

generating, based on the collected patient information, one or more patient values comprising the feature vector;

training a machine learning model based on the feature vector and an associated diagnosis of the patient tissue, the machine learning model comprising a classifier having a weighted value assigned to each of the plurality of feature values, the plurality of color feature values, and the patient value.

8 . The computer-implemented method of claim 7 , further comprising:

defining, based on the training, a bio-marker that identifies one or more of the color value, the patient value, and at least one of the plurality of feature values, the bio-marker being part of the trained classifier for determining a diagnosis of an undiagnosed tissue captured in an undiagnosed three-dimensional image.

9 . The computer-implemented method of claim 8 , wherein the diagnosis includes whether the undiagnosed tissue is malignant or benign.

10 . The computer-implemented method of claim 8 , wherein the undiagnosed tissue is lung tissue or breast tissue.

11 . The computer-implemented method of claim 7 , wherein the three-dimensional image includes a part of a captured three-dimensional image generated by a three-dimensional imaging system.

12 . The computer-implemented method of claim 7 , wherein the three-dimensional image is projected onto at least two different dimensional planes thereby generating at least two different two-dimensional grayscale images.

13 . A non-transitory computer-readable storage medium including program code which when executed by at least one processor causes operations comprising:

projecting a three-dimensional image of a patient tissue into a plurality of two-dimensional grayscale images;

applying at least one transformation algorithm to a first set of two-dimensional grayscale images to generate a first set of transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images of the first set of transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to at least one two-dimensional grayscale image and to each transformed two-dimensional grayscale images, a plurality of feature values comprising a feature vector;

projecting the three-dimensional image into a two-dimensional color image;

applying at least one color transformation algorithm to a first set of two-dimensional color images to generate a first set of color-transformed two-dimensional grayscale images;

applying at least one feature algorithm to at least one two-dimensional color image and to each color-transformed two-dimensional grayscale images;

generating, based on the applying of the at least one feature algorithm to the at least one two-dimensional color image and to each of the transformed two-dimensional color images, a plurality of color feature values comprising the feature vector;

collecting patient information;

generating, based on the collected patient information, one or more patient values comprising the feature vector;

training a machine learning model based on the feature vector and an associated diagnosis of the patient tissue, the machine learning model comprising a classifier having a weighted value assigned to each of the plurality of feature values, the plurality of color feature values, and the patient value.

14 . The computer-readable storage medium of claim 13 , further comprising:

defining, based on the training, a bio-marker that identifies one or more of the color value, the patient value, and at least one of the plurality of feature values, the bio-marker being part of the trained classifier for determining a diagnosis of an undiagnosed tissue captured in an undiagnosed three-dimensional image.

15 . The computer-readable storage medium of claim 14 , wherein the diagnosis includes whether the undiagnosed tissue is malignant or benign.

16 . The computer-readable storage medium of claim 14 , wherein the undiagnosed tissue is lung tissue or breast tissue.

17 . The computer-readable storage medium of claim 13 , wherein the three-dimensional image includes a part of a captured three-dimensional image generated by a three-dimensional imaging system.

18 . The computer-readable storage medium of claim 13 , wherein the three-dimensional image is projected onto at least two different dimensional planes thereby generating at least two different two-dimensional grayscale images.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2021
From: MINDSHARE MEDICAL, INC.
To: PRECISION MEDICAL VENTURES, INC.
Reel/Frame 056085/0033 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 26, 2018
From: CALHOUN, MICHAEL E.; CHOWDHURY, SAMIR; GOLDBERG, ILYA
To: MINDSHARE MEDICAL, INC.
Reel/Frame 046983/0672 →