IP Library Granted Patent US 11,125,720
Granted Patent B2
US 11,125,720 · App. 16/083,780 · Granted Sep 21, 2021

Capillary electrophoresis apparatus

Inventors: Taro Nakazawa (Tokyo, JP); Motohiro Yamazaki (Tokyo, JP); Kenko Uchida (Tokyo, JP); Akira Fujii (Tokyo, JP)
Assignee: Hitachi High-Tech Corporation
G01N27/44791G01N27/44704G01N27/44713
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,125,720
App. No.
16/083,780
Granted
Sep 21, 2021
Kind
B2
Abstract

A capillary electrophoresis apparatus is disclosed that does not discharge and achieves both compactness and performance even with a part configuration having insufficient spatial distance or creeping distance. This capillary electrophoresis apparatus is provided with a resistance heater for heating capillaries, an electrode holder that holds capillary electrodes and is connected to a high-voltage unit, and a conductive member that at least partially comprises metal and has been grounded to a low potential. The electrode holder and conductive member are in contact with heat-dissipating rubber disposed there between that composes a structure comprising an insulation member. As a result of this configuration, discharge risk is reduced through the reduction of the potential of parts near the high-voltage unit and the slow reduction of the high potential of the high-voltage unit.

Claims (31)

1. A capillary electrophoresis apparatus for analyzing a sample by electrophoresis using a capillary, the apparatus comprising:

a heater that heats the capillary;

an electrode holder that holds capillary electrodes of the capillary and is connected to a high-voltage unit; and

a conductive member that is at least partially formed of metal and is grounded to a low potential, wherein

the electrode holder holds a cathode therein,

both the electrode holder and the conductive member are in direct contact with a structure disposed therebetween,

the structure is a rubber, and

a shape of the structure is complementary to an entirety of: i) a shape of the electrode holder, and ii) a shape of the conductive member.

2. The capillary electrophoresis apparatus according to claim 1 , wherein

the conductive member is subjected to insulation treatment.

3. The capillary electrophoresis apparatus according to claim 2 , wherein

the insulation treatment of the conductive member is performed according to a distance from the electrode holder.

4. The capillary electrophoresis apparatus according to claim 1 , wherein

the capillary and the conductive member are in continuous contact with the structure disposed therebetween.

5. The capillary electrophoresis apparatus according to claim 1 , wherein

the structure is constituted of a single layer or a plurality of layers.

6. The capillary electrophoresis apparatus according to claim 1 , wherein

the conductive member has an area larger than an area of a member to which a high voltage is applied by the capillary electrode.

7. The capillary electrophoresis apparatus according to claim 1 , wherein

the conductive member is chamfered.

8. The capillary electrophoresis apparatus according to claim 1 , wherein

the conductive member is constituted of a conductive heat storage plate.

9. The capillary electrophoresis apparatus according to claim 1 , wherein

a non-conductive heat storage plate is arranged between the conductive member and the structure.

10. A capillary electrophoresis apparatus for analyzing by electrophoresis using a capillary, the apparatus comprising:

a heater that heats the capillary;

an electrode holder that holds capillary electrodes of the capillary and is connected to a high-voltage unit; and

a conductive heat storage plate that is at least partially formed of metal and is grounded to a low potential, wherein

the electrode holder and the conductive heat storage plate are in direct continuous contact with a single structure or a plurality of structures disposed therebetween,

the entire structure is an insulation member, and

a shape of the entire structure is complementary to an entirety of: i) a shape of the electrode holder, and ii) a shape of the conductive heat storage plate.

Assignments (3)
CHANGE OF NAME Recorded Apr 14, 2020
From: HITACHI HIGH-TECHNOLOGIES CORPORATION
To: HITACHI HIGH-TECH CORPORATION
Reel/Frame 052398/0249 →
CORRECTIVE ASSIGNMENT TO CORRECT THE EXECUTION DATE FOR 4TH INVENTOR PREVIOUSLY RECORDED AT REEL: 046851 FRAME: 0320. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Nov 29, 2018
From: NAKAZAWA, TARO; YAMAZAKI, MOTOHIRO; UCHIDA, KENKO; FUJII, AKIRA
To: HITACHI HIGH-TECHNOLOGIES CORPORATION
Reel/Frame 047684/0339 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2018
From: NAKAZAWA, TARO; YAMAZAKI, MOTOHIRO; UCHIDA, KENKO; FUJII, AKIRA
To: HITACHI HIGH-TECHNOLOGIES CORPORATION
Reel/Frame 046851/0320 →
Continuity (1)
Related Publication 20190041359A1 · Feb 7, 2019