Treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders with ALPHA5-containing GABAA receptor agonists
Provided herein are alpha5-containing GABA A receptor agonists and pharmaceutical compositions and methods of treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders using them.
1. A compound selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.
2. The compound of claim 1 that is
or a pharmaceutically acceptable salt thereof.
3. The compound of claim 1 that is
or a pharmaceutically acceptable salt thereof.
4. The compound of claim 1 that is
or a pharmaceutically acceptable salt thereof.
5. A pharmaceutical composition comprising the compound according to claim 2 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
6. A pharmaceutical composition comprising the compound according to claim 3 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.
7. A pharmaceutical composition comprising the compound according to claim 4 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.