Process for preparing oxathiazin-like compounds
Oxathiazin-like compounds, processes for making new oxathiazin-like compounds, compounds useful for making oxathiazin-like compounds, and their uses are disclosed. Processes for efficient and safe manufacture of compounds useful for making oxathiazin-like compounds useful for treating patients suffering from cancers, bacterial infections, fungal infections and/or viral infections by administering oxathiazin-like compounds are also disclosed.
1. A process comprising reacting isethionic acid or a salt thereof with benzyl alcohol to produce a compound having structure
or a salt thereof.
2. The process of claim 1 , comprising using sodium hydroxide as a catalyst.
3. The process of claim 1 , wherein the salt of isethionic acid is isethionic acid sodium salt.
4. The process of claim 1 , wherein
is produced.
5. A process for preparing compound 2250 comprising the following reaction steps:
6. A process for preparing compound 2250 comprising the following reaction steps:
7. The process of claim 1 , wherein said reaction is performed at a temperature between 160° C. and 190° C.
8. The process of claim 1 , wherein said reaction is performed at a temperature between 170° C. and 180° C.
9. The process of claim 1 , wherein said reaction is performed at a temperature between 130° C. and 140° C. under vacuum.