IP Library › Granted Patent US 11,116,406
Granted Patent B2
US 11,116,406 · App. 16/093,017 · Granted Sep 14, 2021

Device and Method for increased light transmission through cochlear bone by laser ablation for in situ intracochlear imaging

Inventors: Demetri Psaltis (Préverenges, CH); Konstantina Stankovic (Boston, MA); Donald Benjaman Conkey (Lonay, CH); Marilisa Romito (Lausanne, CH)
Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL); MASSACHUSETTS EYE AND EAR INFIRMARY
A61B5/0066A61B5/0068A61B5/0071A61B18/203A61B2017/00057A61B2018/00327A61B2018/00577
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Quick Facts
Patent No.
US 11,116,406
App. No.
16/093,017
Granted
Sep 14, 2021
Kind
B2
Abstract

A method for visualizing structures inside a cochlea, comprising the steps of irradiating a cochlear bone with a first laser light to ablate portions of the cochlear bone, to form a thinned area of the cochlear bone, and imaging intracochlear structures by a second light via the thinned area of the cochlear bone to optically scan targeted structures inside the cochlea.

Claims (16)

1. A method for visualizing structures inside a cochlea, comprising the steps of:

irradiating a cochlear bone with a first laser light to ablate portions of the cochlear bone, to form a thinned area of the cochlear bone; and

imaging intracochlear structures by optical coherence tomography with a second light via the thinned area of the cochlear bone to optically scan targeted structures inside the cochlea.

2. The method according to claim 1 , further comprising the step of:

measuring a thickness of the thinned area of the cochlear bone with the optical coherence tomography.

3. The method according to claim 1 , further comprising the step of:

applying an optical clearing agent to the cochlear bone before the step of imaging.

4. The method according to claim 1 , further comprising the step of:

filling the thinned area of the cochlear bone with a bone cement, after the step of imaging.

5. The method according to claim 1 , further comprising the step of:

measuring and compensating for scattered light caused by the thinned area of the cochlear bone to adjust scatter and improve focus quality and intensity of the second light.

6. The method according to claim 1 , wherein the step of irradiating and the step of imaging are performed in vivo.

7. A system for removing bone from a cochlea, comprising:

a laser ablation device providing focused laser pulses for removing bone structure to form a thinned area of the cochlear bone; and

an optical coherence tomography device to measure a bone thickness of the thinned area of the cochlear bone.

8. The system according to claim 7 , wherein the focused laser pulses are smaller than 10 ps.

Assignments (2)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE'S DATA PREVIOUSLY RECORDED ON REEL 048775 FRAME 0236. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Feb 6, 2020
From: PSALTIS, DEMETRI; STANKOVIC, KONSTANTINA; CONKEY, DONALD BENJAMAN; ROMITO, MARILISA
To: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL); MASSACHUSETTS EYE AND EAR INFIRMARY
Reel/Frame 051839/0866 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 2, 2019
From: PSALTIS, DEMETRI; STANKOVIC, KONSTANTINA; CONKEY, DONALD BENJAMIN; ROMITO, MARILISA
To: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL); MASSACHUSETTS EYE & EAR INFIRMY
Reel/Frame 048775/0236 →
Continuity (2)
Provisional Application 62322830 · Apr 15, 2016
Related Publication 20190200868A1 · Jul 4, 2019