HYALURONIC ACID COMPOSITION
An injectable hyaluronic acid composition including a hyaluronic acid; a local anesthetic selected from the group consisting of amide and ester type local anesthetics or a combination thereof; and an ascorbic acid derivative in an amount which prevents or reduces the effect on the viscosity and/or elastic modulus G′ of the composition caused by the local anesthetic upon sterilization by heat. Further, the medical and non-medical, such as cosmetic, use of such a composition, and to a method of manufacturing such a composition.
1 . An injectable hyaluronic acid composition comprising
a hyaluronic acid,
a local anesthetic selected from the group consisting of amide and ester type local anesthetics or a combination thereof, and
an ascorbic acid derivative in an amount which prevents or reduces the effect on the viscosity and/or elastic modulus G′ of the composition caused by the local anesthetic upon sterilization by heat.