IP Library Granted Patent US 10,729,772
Granted Patent B2
US 10,729,772 · App. 16/148,467 · Granted Aug 4, 2020

Trace elements

Inventors: Robert Naylor Laurie (Somerset West, ZA); William Alfred Smith (Porterville, CA)
Assignee: WARBURTON TECHNOLOGY LIMITED
A61K45/06A61K31/28A61K33/00A61K33/04A61K33/24A61K33/26A61K33/30A61K33/32A61K33/34Y10S424/06Y10S514/836
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Quick Facts
Patent No.
US 10,729,772
App. No.
16/148,467
Granted
Aug 4, 2020
Kind
B2
Abstract

A trace element solution comprises selenium, zinc, manganese and iron at a concentration of at least 60 mg/ml. The solution may further comprise at least one compound selected from the group comprising iodine, potassium iodide, sodium iodide, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA and sodium hydroxide.

Claims (18)

1. An injectable trace element solution, said solution comprising:

(a) selenium;

(b) zinc;

(c) manganese; and

(d) iron,

wherein a total concentration of selenium, zinc, manganese and iron in the solution is at least 60 mg/ml.

2. The solution of claim 1 , wherein the concentration of selenium in the solution is 5 to 10 mg/ml.

3. The solution of claim 1 , wherein the concentration of zinc in the solution is 35 to 50 mg/ml.

4. The solution of claim 1 , further comprising at least one of copper and chromium.

5. The solution of claim 1 , further comprising at least one compound selected from the group consisting of iodine, potassium iodide, sodium iodide, iron chloride, zinc oxide, manganese sulphate, sodium selenite, copper carbonate, sodium carbonate, anhydrous disodium EDTA and sodium hydroxide.

6. The solution of claim 5 , wherein at least one of the metals is provided in the form of an EDTA complex.

7. The solution of claim 6 , wherein the EDTA complex is produced from at least one compound selected from the group consisting of sodium EDTA and potassium EDTA.

8. The solution of claim 1 , further comprising chlorocresol as preservative.

9. The solution of claim 1 , further comprising 5-10 mg/ml chromium.

10. The solution of claim 1 , wherein the iron in solution is 5-50 mg/ml.

11. The solution of claim 1 , further comprising 20-400 mg/ml iodine.

12. The solution of claim 1 , wherein the selenium is present in an amount of 5 mg/ml.

13. The solution of claim 1 , further comprising 5-10 mg/ml chromium.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Feb 13, 2026
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION (AS SUCCESSOR IN INTEREST TO U.S. BANK NATIONAL ASSOCIATION), AS ADMINISTRATIVE AGENT
To: AXIOTA U.S., INC. (F/K/A MS BIOTECH, INC.); WARBURTON TECHNOLOGY LIMITED
Reel/Frame 073791/0089 →
ASSIGNMENT AND ASSUMPTION AGREEMENT Recorded Mar 17, 2023
From: U.S. BANK NATIONAL ASSOCIATION
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 063115/0486 →
SECURITY INTEREST Recorded Dec 24, 2019
From: WARBURTON TECHNOLOGY LIMITED
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051363/0001 →
Continuity (3)
Continuation 11861724 · Sep 26, 2007
Division 10834094 · Apr 29, 2004
Related Publication 20190030164A1 · Jan 31, 2019