IP Library Granted Patent US 11,318,077
Granted Patent B2
US 11,318,077 · App. 16/148,768 · Granted May 3, 2022

Retinaldehyde containing compositions and methods of use

Inventors: Kathy Ann Fields (San Francisco, CA); Kathryn Pregerson Rodan (Oakland, CA); George Paul Majewski (Emeryville, CA); Timothy John Falla (Woodinville, WA); Robert Bianchini (Dana Point, CA)
Assignee: RODAN & FIELDS, LLC
A61K8/34A61K8/24A61K8/37A61K8/585A61K8/64A61K8/671A61K8/891A61K31/07A61K31/08A61K31/192A61K31/203A61Q19/08A61K2800/874
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,318,077
App. No.
16/148,768
Granted
May 3, 2022
Kind
B2
Abstract

This disclosure is directed to compositions comprised of retinaldehyde, one or more skin conditioning agents, and, optionally, one or more additional retinoids. This disclosure is directed. Embodiments are also directed to compositions comprised of retinaldehyde, one or more peptides, one or more skin conditioning agents, one or more calcium containing agents, and, optionally, one or more additional retinoids. Embodiments are also directed to compositions comprised of retinaldehyde, one or more peptides, one or more skin conditioning agents, one or more calcium containing agents, and, optionally, one or more additional retinoids. Additional embodiments disclose methods for treating the skin wherein a characteristic of the skin is improved, the characteristics include firmness, elasticity, fine lines and wrinkles, skin texture, dullness, dyschromia, skin tone, reduction or elimination of acne, and any combination thereof. This disclosure is also directed to kits used for treating the skin with the compositions described herein.

Claims (17)

1. A method of treating skin comprising:

topically applying a composition to skin of a subject, wherein the composition comprises: retinaldehyde, palmitoyl hexapeptide-14, one or more skin conditioning agents selected from cyclopentasiloxane, dimethicone, polysilicone-11, ethylhexyl hydroxystearate, C12-15 alykl benzoate, bis-ethylhexyl hydroxydimethoxy, benzylmalonate, ethoxydiglycol, or combinations thereof, hydroxyapatite, and, retinyl palmitate,

wherein treating the skin is an improvement in a characteristic of the skin selected from the group consisting of firmness, elasticity, fine lines and wrinkles, skin texture, dullness, dyschromia, skin tone, reduction or elimination of acne, and any combination thereof, and

wherein the improvement in a characteristic of the skin of the subject is achieved after 4 weeks of treatment with the composition.

2. The method of claim 1 , wherein the composition further comprises one or more additional retinoids selected from the group consisting of alitretinoin (9-cis-retinoic acid), tretinoin (all-trans-retinoic acid), isotretinoin (13-cis-retinoic acid), etretinate, acitretin, adapalene, bexarotene, tazarotene, hydroxypinacolone retinoate (HPR), retinoid ester, retinoate, and derivatives and combinations thereof.

3. The method of claim 1 , wherein the composition further comprises one or more skin conditioning agents selected from the group consisting of hyaluronic acid, alpha hydroxyl acids, glycolic acid, lactic acid, ascorbic acid, polyhydroxy acids, gluconolactone, lactobionic acid, beta hydroxyl acid, peat extract, glycine, cetyl alcohol, stearyl alcohol, and derivatives and combinations thereof.

4. The method of claim 1 , wherein the composition further comprises one or more peptides selected from the group consisting of oligopeptide-10, myristoyl pentapeptide-8, myristoyl tetrapeptide-8, sericin, silk protein, collagen, keratin, amino acids, hexapeptide-21, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, tetrapeptide-16, polyacrylate-13, polyisobutene, polysorbate-20, betaine, milk solids, rice peptides, and derivatives and combinations thereof.

5. The method of claim 1 , wherein the composition further comprises one or more calcium containing agents selected from the group consisting of calcium lactate, calcium chloride, calcium carbonate, calcium phosphate, calcium pyrophosphate, calcium sulfate, dicalcium phosphate, dicalcium phosphate dehydrate, tricalcium phosphate, calcium undecylenate, and derivatives and combinations thereof.

6. The method of claim 1 , wherein the composition comprises retinaldehyde, cyclopentasiloxane, dimethicone, polysilicone-11, ethylhexyl hydroxystearate, C12-15 alkyl benzoate, palmitoyl hexapeptide-14, retinyl palmitate, bis-ethylhexyl hydroxydimethoxy benzylmalonate, hydroxyapatite, and ethoxydiglycol.

7. The method of claim 1 , wherein the method further comprises cleansing the skin with a daily cleansing mask.

8. The method of claim 1 , wherein the method further comprises topically applying a toner to the skin.

9. The method of claim 1 , wherein the method further comprises exfoliating the skin.

10. The method of claim 9 , wherein the exfoliating the skin occurs using a micro-dermabrasion paste, an exfoliating scrub, or an exfoliating tool.

11. The method of claim 1 , wherein the method further comprises rolling the skin with a micro-exfoliation tool.

12. The method of claim 1 , wherein the skin is any skin surface selected from the group consisting of scalp, face, neck, décolletage, back, arms, legs, hands, feet, chest, stomach, and buttocks.

13. The method of claim 1 , wherein a subject shows the improvement in a characteristic of the skin after 8 weeks of treatment.

14. The method of claim 1 , wherein a subject shows the reduction or elimination of acne after 2 weeks of treatment.

Assignments (10)
ASSIGNMENT OF SECURITY INTERESTS IN PATENT COLLATERAL Recorded Feb 2, 2026
From: CITIBANK, N.A., IN ITS CAPACITY AS THE WITHDRAWING AGENT
To: ANKURA TRUST COMPANY, LLC, IN ITS CAPACITY AS SUCCESSOR AGENT
Reel/Frame 074643/0097 →
MERGER Recorded Oct 9, 2024
From: RODAN & FIELDS, LLC
To: RODAN & FIELDS BEAUTY, LLC
Reel/Frame 068844/0351 →
PATENT SECURITY AGREEMENT Recorded Sep 27, 2024
From: RODAN & FIELDS BEAUTY, LLC
To: ANKURA TRUST COMPANY, LLC, AS COLLATERAL AGENT
Reel/Frame 069066/0818 →
RELEASE OF SECURITY INTEREST IN PATENT COLLATERAL RECORDED ON APRIL 28, 2023, AT REEL/FRAME 063480/0786 Recorded Sep 27, 2024
From: ANKURA TRUST COMPANY, LLC, AS COLLATERAL AGENT
To: RODAN & FIELDS, LLC
Reel/Frame 069066/0803 →
PATENT SECURITY AGREEMENT Recorded Sep 27, 2024
From: RODAN & FIELDS BEAUTY, LLC
To: ANKURA TRUST COMPANY, LLC, AS COLLATERAL AGENT
Reel/Frame 069066/0810 →
SECURITY INTEREST Recorded May 2, 2023
From: RODAN & FIELDS, LLC
To: CITIBANK, N.A.
Reel/Frame 063501/0785 →
SECURITY INTEREST Recorded May 2, 2023
From: RODAN & FIELDS, LLC
To: ANKURA TRUST COMPANY, LLC
Reel/Frame 063501/0804 →
SECURITY INTEREST Recorded Apr 28, 2023
From: RODAN & FIELDS, LLC
To: ANKURA TRUST COMPANY, LLC
Reel/Frame 063480/0786 →
SECURITY INTEREST Recorded Apr 28, 2023
From: RODAN & FIELDS, LLC
To: ANKURA TRUST COMPANY, LLC
Reel/Frame 063480/0179 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 11, 2019
From: BIANCHINI, ROBERT; FALLA, TIMOTHY JOHN; FIELDS, KATHY ANN; MAJEWSKI, GEORGE PAUL; RODAN, KATHRYN PREGERSON
To: RODAN & FIELDS, LLC
Reel/Frame 050019/0453 →
Continuity (2)
Provisional Application 62565314 · Sep 29, 2017
Related Publication 20190099340A1 · Apr 4, 2019