IP Library Granted Patent US 10,383,686
Granted Patent B2
US 10,383,686 · App. 16/155,793 · Granted Aug 20, 2019

Ablation systems with multiple temperature sensors

Inventors: Dorin Panescu (San Jose, CA); Eric Andrew Schultheis (Sunnyvale, CA); Josef Vincent Koblish (Sunnyvale, CA); Jessi E. Johnson (Sunnyvale, CA)
Assignee: Epix Therapeutics, Inc.
A61B18/1492A61B5/01A61B5/0422A61B5/068A61B5/150954A61B5/6852A61B18/1206A61B2018/0016A61B2018/00023A61B2018/00029A61B2018/00083A61B2018/00101A61B2018/00351A61B2018/00357A61B2018/00577A61B2018/00642A61B2018/00672A61B2018/00678A61B2018/00702A61B2018/00714A61B2018/00761A61B2018/00797A61B2018/00815A61B2018/00821A61B2018/00839A61B2018/00875A61B2018/128A61B2018/1467A61B2217/007A61B2218/002A61B2562/046
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Quick Facts
Patent No.
US 10,383,686
App. No.
16/155,793
Granted
Aug 20, 2019
Kind
B2
Abstract

According to some embodiments, a medical instrument (for example, an ablation device) comprises an elongate body having a proximal end and a distal end, an energy delivery member positioned at the distal end of the elongate body, a first plurality of temperature-measurement devices carried by or positioned within the energy delivery member, the first plurality of temperature-measurement devices being thermally insulated from the energy delivery member, and a second plurality of temperature-measurement devices positioned proximal to a proximal end of the energy delivery member, the second plurality of temperature-measurement devices being thermally insulated from the energy delivery member.

Claims (54)

1. A cardiac ablation system, comprising:

a catheter comprising an electrode assembly, the electrode assembly comprising a proximal electrode and a distal electrode, wherein the proximal electrode is separated from the distal electrode by a gap; and

an energy delivery device configured to deliver energy at a frequency within an ablation radiofrequency range to the electrode assembly;

wherein the proximal electrode is operatively coupled to the distal electrode using a filtering element at the ablation radiofrequency range such that the proximal electrode and the distal electrode function like a single electrode, and wherein the proximal electrode and the distal electrode function as separate electrodes at high-resolution mapping frequencies;

wherein the system is configured to receive signals indicative of temperature from at least one temperature sensor positioned along the proximal electrode or distal electrode;

wherein the system is configured to determine, upon execution of instructions stored on a non-transitory storage medium by a hardware processor, temperature measurements from the signals received from the at least one temperature sensor; and

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on the determined temperature measurements.

2. The system of claim 1 ,

wherein the ablation radiofrequency range is between 200 kHz and 10 MHz;

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on a predictive model or on at least one peak temperature measurement; and

wherein the at least one temperature sensor is configured to detect tissue temperature.

3. The system of claim 1 ,

wherein the at least one temperature sensor is configured to detect tissue temperature;

wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode; and

wherein the at least one temperature sensor comprises a thermocouple.

4. The system of claim 1 , wherein the ablation radiofrequency range is between 200 kHz and 10 MHz.

5. The system of claim 1 , wherein the system is configured to adjust one or more treatment parameters of the ablation procedure automatically by adjusting a power level.

6. The system of claim 1 , wherein the at least one temperature sensor is configured to detect tissue temperature.

7. The system of claim 1 , wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode.

8. The system of claim 1 , wherein the at least one temperature sensor comprises a thermocouple.

9. The system of claim 1 , wherein the at least one temperature sensor comprises at least three temperature sensors located near the proximal electrode and at least three temperature sensors located near the distal electrode.

10. The system of claim 1 , wherein the filtering element comprises a capacitor.

11. A cardiac ablation system, comprising:

an elongate member comprising a proximal electrode and a distal electrode, wherein the proximal electrode is separated from the distal electrode by a gap; and

an energy delivery device configured to deliver energy at a frequency within an ablation radiofrequency range to at least one of a proximal electrode and a distal electrode;

wherein the proximal electrode is operatively coupled to the distal electrode using a filtering element at the ablation radiofrequency range such that the proximal electrode and the distal electrode function like a single electrode, and wherein the proximal electrode and the distal electrode function as separate electrodes at high-resolution mapping frequencies;

wherein the system is configured to receive signals indicative of temperature from at least one temperature sensor positioned along the proximal electrode or distal electrode;

wherein the system is configured to determine temperature measurements from the signals received from the at least one temperature sensor; and

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on the determined temperature measurements.

12. The system of claim 11 ,

wherein the ablation radiofrequency range is between 200 kHz and 10 MHz; and

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on a predictive model or on at least one peak temperature measurement.

13. The system of claim 11 ,

wherein the at least one temperature sensor is configured to detect tissue temperature;

wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode; and

wherein the at least one temperature sensor comprises a thermocouple.

14. The system of claim 11 , wherein the ablation radiofrequency range is between 200 kHz and 10 MHz.

15. The system of claim 11 , wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode.

16. A cardiac ablation system, comprising:

an elongate member comprising a proximal electrode and a distal electrode, wherein the proximal electrode is adjacent the distal electrode; and

an energy delivery device configured to deliver energy at a frequency within an ablation radiofrequency range to at least one of a proximal electrode and a distal electrode;

wherein the proximal electrode is operatively coupled to the distal electrode using a filtering element at the ablation radiofrequency range such that the proximal electrode and the distal electrode function like a single electrode, and wherein the proximal electrode and the distal electrode function as separate electrodes at high-resolution mapping frequencies;

wherein the system is configured to receive signals indicative of temperature from at least one temperature sensor positioned along the proximal electrode or distal electrode;

wherein the system is configured to determine temperature measurements from the signals received from the at least one temperature sensor; and

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on the determined temperature measurements.

17. The system of claim 16 ,

wherein the ablation radiofrequency range is between 200 kHz and 10 MHz; and

wherein the system is configured to adjust one or more treatment parameters of the ablation procedure based, at least in part, on a predictive model or on at least one peak temperature measurement.

18. The system of claim 16 ,

wherein the at least one temperature sensor is configured to detect tissue temperature;

wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode; and

wherein the at least one temperature sensor comprises a thermocouple.

19. The system of claim 16 , wherein the ablation radiofrequency range is between 200 kHz and 10 MHz.

20. The system of claim 16 , wherein the at least one temperature sensor is thermally insulated from the first electrode and the second electrode.

Assignments (2)
CHANGE OF NAME Recorded Oct 17, 2018
From: ADVANCED CARDIAC THERAPEUTICS, INC.
To: EPIX THERAPEUTICS, INC.
Reel/Frame 047245/0509 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2018
From: PANESCU, DORIN; KOBLISH, JOSEF VINCENT; JOHNSON, JESSI E.; SCHULTHEIS, ERIC ANDREW
To: ADVANCED CARDIAC THERAPEUTICS, INC.
Reel/Frame 047138/0921 →
Continuity (10)
Continuation 15382436 · Dec 16, 2016
Continuation 15214376 · Jul 19, 2016
Continuation PCTUS2015061419 · Nov 18, 2015
Provisional Application 62211539 · Aug 28, 2015
Provisional Application 62138338 · Mar 25, 2015
Provisional Application 62135025 · Mar 18, 2015
Provisional Application 62135046 · Mar 18, 2015
Provisional Application 62094892 · Dec 19, 2014
Provisional Application 62081710 · Nov 19, 2014
Related Publication 20190038347A1 · Feb 7, 2019
Cited By (3)
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