IP Library Granted Patent US 11,284,838
Granted Patent B2
US 11,284,838 · App. 16/169,295 · Granted Mar 29, 2022

Non-invasive wearable biomechanical and physiology monitor for injury prevention and rehabilitation

Inventors: Marissa A. Howard (Richmond, VA); Lance A. Liotta (Bethesda, MD); Rachel Naidich (Fairfax, VA); Matthew Luu Trang (Nokesville, VA); Ish Sethi (Chantilly, VA); Rebecca Woodhouse (Oakton, VA); Kshamata Neupane (Haymarket, VA)
Assignee: George Mason University Research Foundation, Inc.
A61B5/6828A61B5/0024A61B5/0053A61B5/015A61B5/1107A61B5/1126A61B5/4528A61B5/4585A61B5/4848A61B5/6824A61B5/6829A61B5/7275A61B5/746A61B5/0048A61B5/112A61B5/1114A61B5/4519A61B5/7465A61B2503/08A61B2503/10A61B2505/09A61B2562/0219A61B2562/0247A61B2562/0261A61B2562/0271A61H2230/08A61H2230/50
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Quick Facts
Patent No.
US 11,284,838
App. No.
16/169,295
Granted
Mar 29, 2022
Kind
B2
Abstract

A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program.

Claims (30)

1. A method for diagnosing embolism or infection in a subject's leg, comprising

placing a wrap about a knee of a subject, the wrap comprising a plurality of first sensors positionable to sense temperatures about a circumference of a patella of the knee and at least one second sensor positionable to sense temperature at a back of the knee;

comparing temperatures from the first and second temperature sensors; and

identifying a presence of embolism or infection in the subject's leg when the comparison shows an elevation in body temperature at the back of the knee relative to the circumference of the patella.

2. The method of claim 1 , further comprising sending an alert concerning the embolism or infection.

3. The method of claim 2 , wherein the alert is sent to one or more of the subject and a healthcare provider.

4. The method of claim 1 , wherein the subject is a human.

5. A medical apparatus for patients at risk of post-operative thrombosis or infection, comprising

a flexible wrap configured to conform to a knee of a patient's body;

temperature sensors attached or attachable to the flexible wrap, the temperature sensors comprising a first temperature sensor configured to sense a first temperature in a first position on the flexible wrap and a second temperature sensor configured to sense a second temperature in a second position on the flexible wrap, wherein the first position corresponds with a back of the knee and the second position corresponds with a location about a circumference of a patella of the knee;

at least one medial strain gauge and at least one lateral strain gauge attached or attachable to the flexible wrap and configured to sense strain along medial and lateral axes respectively;

at least one processor and storage in communication with the temperature sensors, at least one medial strain gauge, and at least one lateral strain gauge, the storage comprising executable instructions which, when executed by the processor, cause the at least one processor to

detect a localized elevations in body temperature at the first position relative to the second position by monitoring the first and second temperatures sensed respectively by the first and second temperature sensors at the first and second positions on the wrap,

detect swelling by monitoring the strain sensed by the at least one stretch sensor relative to a threshold,

identify a risk of thrombosis or infection when both a localized elevation in body temperature and swelling are detected, and

provide an alert to the patient and/or a heath care professional of the identified risk.

6. The medical apparatus of claim 5 , wherein the processor and storage are on the flexible wrap.

7. The medical apparatus of claim 5 , wherein the processor and storage are remote from and

not on the flexible wrap.

8. The medical apparatus of claim 5 , further comprising one or more of an ultrasound sensor and infrared sensor usable by the at least one processor to monitor platelet buildup.

9. The medical apparatus of claim 5 , further comprising a pressure sensitive patellar position monitor configured to detect pressure about a circumference of the patient's patella and measure patellar deviations.

10. The medical apparatus of claim 5 , wherein the executable instructions, when executed by the at least one processor, further cause the at least one processor to produce a thermal heat map from measurements of the temperature sensors.

11. The medical apparatus of claim 10 , wherein in the localized elevation in body temperature is detected using the thermal heat map.

12. The medical apparatus of claim 5 , wherein the executable instructions comprise a machine learning algorithm which, when executed by the processor, individualizes one or more of the detection, identification, and providing steps based on longitudinal data describing the patient.

13. The medical apparatus of claim 5 , wherein the patient is a human or a mammal in the family Equidae.

14. A method for monitoring a patient for post-operative thrombosis or infection, comprising

monitoring a first temperature at a back of a knee with a first temperature sensor;

monitoring a second temperature at a second position different than the back of the knee joint with a second temperature sensor, wherein the second position corresponds with a location about a circumference of a patella of the knee joint;

monitoring medial and lateral strain by the knee joint with at least one medial strain gauge and at least one lateral strain gauge respectively;

providing an alert of a risk of thrombosis or infection from detection of both a localized elevation in body temperature at the back of the knee joint relative to the second position and swelling indicated by an increase in either the medial or lateral strain relative to a threshold.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2019
From: GEORGE MASON UNIVERSITY
To: GEORGE MASON RESEARCH FOUNDATION, INC.
Reel/Frame 048467/0349 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2018
From: HOWARD, MARISSA; LIOTTA, LANCE; NEUPANE, KSHAMATA; TRANG, MATTHEW LUU; NAIDICH, RACHEL; SETHI, ISH; WOODHOUSE, REBECCA
To: GEORGE MASON UNIVERSITY
Reel/Frame 047793/0444 →
CONFIRMATORY LICENSE Recorded Dec 4, 2018
From: GEORGE MASON UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 047664/0187 →
Continuity (2)
Provisional Application 62576361 · Oct 24, 2017
Related Publication 20190117156A1 · Apr 25, 2019