Patterned stimulation intensity for neural stimulation
One aspect of the present disclosure relates to a system that can modulate the intensity of a neural stimulation signal over time. A pulse generator can be configured to generate a stimulation signal for application to neural tissue of an individual and modulate a parameter related to intensity of a pattern of pulses of the stimulation signal over time. An electrode can be coupled to the pulse generator and configured to apply the stimulation signal to the neural tissue. A population of axons in the neural tissue can be recruited with each pulse of the stimulation signal.
1. A method for providing artificial sensation comprising:
determining a virtual sensation to be felt by an individual based on a stimulation, wherein the stimulation is related to a touch-enabled virtual reality without the individual physically experiencing a stimulus related to the virtual sensation;
configuring a stimulation signal with a pattern of stimulation intensities based on the virtual sensation to be felt by the individual; and
delivering the stimulation signal with the pattern of stimulation intensities to one or more peripheral nerves to cause the individual to experience the virtual sensation.
2. The method of claim 1 , further comprising:
receiving a feedback signal based on the virtual sensation; and
reconfiguring the stimulation signal with a new pattern of stimulation intensities based on the feedback signal.
3. The method of claim 1 , wherein the one or more peripheral nerves comprise a median nerve, an ulnar nerve, and/or a radial nerve.
4. The method of claim 1 , wherein individual is an able-bodied individual, an amputee, a paralyzed individual, or a diseased individual.
5. The method of claim 1 , wherein the touch-enabled virtual reality is related to a user interface, a clinical diagnosis, a mechanical diagnosis, a robotic control, and/or a telepresence.
6. A system comprising:
a pulse generator configured to:
receive a signal comprising information related to a virtual sensation to be felt by an individual based on a stimulation, wherein the stimulation is related to a touch-enabled virtual reality without the individual physically experiencing a stimulus related to the virtual sensation;
configure a stimulation signal with a pattern of stimulation intensities based on the virtual sensation to be felt by the individual; and
generate the stimulation signal with the pattern of stimulation intensities; and
an electrode coupled to the pulse generator and configured deliver the stimulation signal to one or more peripheral nerves to cause the individual to experience the virtual sensation.
7. The system of claim 6 , further comprising a receiver to receive a feedback signal based on the virtual sensation,
wherein the pulse generator is configured to reconfigure the stimulation signal with a new pattern of stimulation intensities based on the feedback signal.
8. The system of claim 7 , wherein the stimulation signal comprises a plurality of pulses, and
wherein the pattern of stimulation intensities comprises at least one parameter that is variable for each of the plurality of pulses.
9. The system of claim 8 , wherein the pulse generator is configured to vary the at least one parameter for each of the plurality of pulses in the stimulation signal.
10. The system of claim 7 , wherein the feedback signal is related to a change to the stimulation.
11. The system of claim 10 , wherein the change in the stimulation causes the virtual sensation to be altered.
12. The system of claim 6 , wherein the touch-enabled virtual reality is related to a user interface, a clinical diagnosis, a mechanical diagnosis, a robotic control, and/or a telepresence.