Goggle imaging systems and methods
A compound of formula (I) is provided having the structure: cypate-cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH, and each amino acid is independently in a D or L configuration. Also provided are pharmaceutical compositions that include the compound of formula (I) and its use in treating cancer by administering it to a patient in need thereof.
1. A compound of formula (I), or a salt thereof,
cypate-cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH (I)
wherein each amino acid is independently in a D or L configuration.
2. The compound according to claim 1 , wherein the cypate is
3. The compound of formula (I) according to claim 1 , wherein at least one of the Cys amino acid residues is D-Cys.
4. The compound of formula (I) according to claim 1 having the formula:
5. The compound of formula (I) according to claim 1 , wherein the compound is LS-301:
6. A pharmaceutical composition comprising:
the compound of formula (I) according to claim 1 , or a pharmaceutically acceptable salt thereof, and
a pharmaceutically acceptable carrier.
7. The pharmaceutical composition according to claim 6 , wherein said composition is in a formulation suitable for intravenous administration.
8. The pharmaceutical composition according to claim 6 , wherein the compound is LS-301.
9. The compound of formula (I) according to claim 1 , wherein the compound is