Granted Patent
B2
US 10,745,358 · App. 16/195,997 · Granted Aug 18, 2020
Oxoacridinyl acetic acid derivatives and methods of use
Inventors:
Brian T. Chamberlain (Wilmington, DE); James M. Rice (Wilmington, DE); Finith E. Jernigan, III (Wilmington, DE); Woody Sherman (Wilmington, DE); Meghana M. Kulkarni (Wilmington, DE); Sharon Shechter (Wilmington, DE); Bryce K. Allen (Wilmington, DE); Dazhi Tan (Wilmington, DE); Kristen A. Marino (Wilmington, DE); Zhixiong Lin (Wilmington, DE)
Assignee:
Silicon SWAT, Inc.
C07D219/06C07D209/86C07D209/88C07D219/08C07D401/04C07D401/12C07D405/04C07D405/12C07D413/04C07D417/04
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Abstract
Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
Claims (5)
1. A compound of the following formula
or a pharmaceutically acceptable salt or ester thereof.
2. A compound of the following formula
or a pharmaceutically acceptable salt thereof.
3. A compound of the following formula
Assignments (2)
CHANGE OF NAME
Recorded May 21, 2026
From: SILICON SWAT, INC.
To: STINGTHERA, INC.
Reel/Frame 075630/0903 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 20, 2018
From: CHAMBERLAIN, BRIAN T.; RICE, JAMES M.; JERNIGAN, FINITH E., III; SHERMAN, WOODY; KULKARNI, MEGHANA M.; SHECHTER, SHARON; ALLEN, BRYCE K.; TAN, DAZHI; MARINO, KRISTEN A.; LIN, ZHIXIONG
To: SILICON SWAT, INC.
Reel/Frame 047825/0976 →
Continuity (4)
Provisional Application
62723660
· Aug 28, 2018
Provisional Application
62631530
· Feb 16, 2018
Provisional Application
62588820
· Nov 20, 2017