Granted Patent
B2
US 10,626,111 · App. 16/197,732 · Granted Apr 21, 2020
Modulators of ATP-binding cassette transporters
Inventors:
Sara S. Hadida Ruah (La Jolla, CA); Matthew M. Hamilton (Hackettstown, NJ); Mark Miller (San Diego, CA); Peter D. J. Grootenhuis (San Diego, CA)
Assignee:
Vertex Pharmaceuticals Incorporated
C07D405/12A61K31/443A61K31/444A61K31/4545A61K31/47A61K31/4709A61K31/496A61K31/497A61K31/501A61K31/506A61K31/5377A61K45/06C07D317/12C07D405/14
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Abstract
Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTC”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
Claims (1)
1. A compound having the chemical structure:
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 15, 2019
From: RUAH, SARA HADIDA; HAMILTON, MATTHEW; MILLER, MARK; GROOTENHUIS, PETER
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 049747/0882 →
CHANGE OF ADDRESS
Recorded Jul 15, 2019
From: VERTEX PHARMACEUTICALS INCORPORATED
To: VERTEX PHARMACEUTICALS INCORPORATED
Reel/Frame 049748/0211 →
Continuity (15)
Continuation
14994487
· Jan 13, 2016
Continuation
PCTUS2006043289
· Nov 8, 2006
Provisional Application
60802458
· May 22, 2006
Provisional Application
60754086
· Dec 27, 2005
Provisional Application
60734506
· Nov 8, 2005
Provisional Application
60603503
· Aug 20, 2004
Provisional Application
60540564
· Jan 30, 2004