Methods and materials for treating cancer
This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided.
1. A method of treating cancer within a mammal, wherein said method comprises administering to said mammal a composition comprising nucleic acid encoding an HIF-2α antigen, a SOX-10 antigen, and a C-MYC antigen, wherein said composition comprises less than 100 separate nucleic acid molecules.
2. The method of claim 1 , wherein said cancer is a melanoma.
3. The method of claim 1 , wherein said HIF-2α antigen, said SOX-10 antigen, and said C-MYC antigen are VSV-expressed.