IP Library › Granted Patent US 10,640,510
Granted Patent B2
US 10,640,510 · App. 16/211,338 · Granted May 5, 2020

Metabotrophic glutamate receptor 5 modulators and methods use thereof

Inventors: Michele L. R. Heffernan (Worcester, MA); Larry Wendell Hardy (Sturbridge, MA); Frank Xinhe Wu (Shrewsbury, MA); Lakshmi D. Saraswat (Sudbury, MA); Kerry L. Spear (Concord, MA)
Assignee: SUNOVION PHARMACEUTICALS INC.
C07D487/04C07D471/04C07D471/14C07D471/20C07D487/10C07D487/14C07D487/18C07D491/147C07D491/20C07D491/22C07D498/04
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Quick Facts
Patent No.
US 10,640,510
App. No.
16/211,338
Granted
May 5, 2020
Kind
B2
Abstract

Compounds that modulate GluR5 activity and methods of using the same are disclosed.

Claims (12)

1. A compound, wherein said compound is:

or a pharmaceutically acceptable salt thereof.

2. The compound according to claim 1 , wherein said compound is:

or a pharmaceutically acceptable salt thereof.

3. The compound according to claim 1 , wherein said compound is:

or a pharmaceutically acceptable salt thereof.

4. A method of treating Fragile X, comprising the step of administering the compound:

or a pharmaceutically acceptable salt thereof, to a patient or subject in need thereof.

5. The method according to claim 4 , wherein said compound is:

or a pharmaceutically acceptable salt thereof.

6. The method according to claim 4 , wherein said compound is:

or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2020
From: HEFFERNAN, MICHELE L.R.; HARDY, LARRY WENDELL; WU, FRANK XINHE; SARASWAT, LAKSHMI D.; SPEAR, KERRY L.
To: SUNOVION PHARMACEUTICALS INC.
Reel/Frame 052157/0991 →
Continuity (6)
Continuation 15625604 · Jun 16, 2017
Continuation 15013741 · Feb 2, 2016
Division 14124455
Provisional Application 61494731 · Jun 8, 2011
Related Publication 20190135815A1 · May 9, 2019
Related Publication 20200079778A9 · Mar 12, 2020