IP Library › Patent Application 16220269
Patent Application
App. No. 16/220,269

LOW DOSE TOPIRAMATE/PHENTERMINE COMPOSITION AND METHODS OF USE THEREOF

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Patent No.
US None
App. No.
16/220,269
Abstract

A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in the range of 2 mg to 8 mg, in combination with a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone. Methods for treating obesity, conditions associated with obesity, and other indications are also provided, as are compositions and dosage forms containing low doses of phentermine and topiramate, e.g., 3.75 mg phentermine and 23 mg topiramate.

Claims (3)

1 . A controlled release composition for treating obesity, diabetes, sleep apnea, or a related condition in a subject comprising:

an effective amount of topiramate and phentermine.

2 . A method for effecting weight loss in a subject, comprising administering to the subject continually over a significant period of time a daily dose of phentermine in combination therewith a daily dose of topiramate selected to prevent the loss of effectiveness of phentermine alone.

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jan 6, 2021
From: U.S. BANK NATIONAL ASSOCIATION
To: VIVUS, INC.
Reel/Frame 054835/0633 →
SECURITY INTEREST Recorded Sep 30, 2019
From: VIVUS, INC.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 050570/0289 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 17, 2018
From: NAJARIAN, THOMAS; TAM, PETER Y.; WILSON, LELAND F.
To: VIVUS, INC.
Reel/Frame 047790/0064 →