IP Library › Patent Application 16225991
Patent Application
App. No. 16/225,991

Substituted Chromanes and Method of Use

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Quick Facts
Patent No.
US None
App. No.
16/225,991
Abstract

The invention provides for compounds of formula (I) wherein R 1 , X, Y, R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , m, and R″ have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sjögren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).

Claims (3)

1 . A compound having the formulae:

or a pharmaceutically acceptable salt thereof;

wherein one or more hydrogen atoms of the compound are replaced by deuterium.

Assignments (1)
MERGER Recorded May 13, 2020
From: ABBVIE S.Á.R.L.
To: ABBVIE OVERSEAS S.Á.R.L.
Reel/Frame 052647/0794 →