Lysophosphatidylcholine compositions
The present invention provides marine lysophosphatidylcholine compositions for use in pharmaceuticals, nutraceuticals and functional foods, as well as methods for making marine lysophosphatidylcholine compositions.
1. A marine lysophosphatidylcholine (LPC) composition characterized in comprising from about 20% to about 100% LPC w/w of the composition and an omega-3 fatty acid content of from 5% to 50% w/w of the composition, a ratio of EPA:DHA of from 1:1 to 3:1 on a w/w basis or a ratio of DHA:EPA of from 1:1 to 5:1 on a w/w basis, and a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis.
2. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition comprises from 60% to 100% LPC w/w of the composition.
3. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has an omega-3 fatty acid content of from 30% to 50% w/w of the composition.
4. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition comprises from 70% to 90% LPC w/w of the composition.
5. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has an omega-3 fatty acid content of from 35% to 45% w/w of the composition.
6. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition comprises from 20% to 50% LPC w/w of the composition.
7. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition comprises from 20% to 30% LPC w/w of the composition.
8. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has an omega-3 fatty acid content of from 5% to 20% w/w of the composition.
9. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has a phosphatidylcholine (PC) content of less than 10% w/w of the composition.
10. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition.
11. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has a neutral lipid content of from 5% to 65% w/w of the composition.
12. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition has a 2-LPC ether content of less than 1.0% w/w of the composition.
13. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition additionally has two or more of the following properties:
a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis;
a phosphatidylcholine (PC) content of less than 10% w/w of the composition; and
a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition.
14. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition additionally has two or more of the following properties:
a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis;
a phosphatidylcholine (PC) content of less than 10% w/w of the composition;
a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition;
a neutral lipid content of from 5% to 65% w/w of the composition; and
a 2-LPC ether content of less than 1.0% w/w of the composition.
15. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition additionally has three or more of the following properties:
a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis;
a phosphatidylcholine (PC) content of less than 10% w/w of the composition;
a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition;
a neutral lipid content of from 5% to 65% w/w of the composition; and
a 2-LPC ether content of less than 1.0% w/w of the composition.
16. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition additionally has four or more of the following properties:
a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis;
a phosphatidylcholine (PC) content of less than 10% w/w of the composition;
a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition;
a neutral lipid content of from 5% to 65% w/w of the composition; and
a 2-LPC ether content of less than 1.0% w/w of the composition.
17. The marine lysophosphatidylcholine (LPC) composition of claim 1 , wherein the composition additionally has the following properties:
a 2-LPC:1-LPC ratio of from 1:8 to 18:1 on a w/w basis;
a phosphatidylcholine (PC) content of less than 10% w/w of the composition;
a phosphatidylethanolamine (PE) content of less than 1.2% w/w of the composition;
a neutral lipid content of from 5% to 65% w/w of the composition; and
a 2-LPC ether content of less than 1.0% w/w of the composition.