Patent Application
App. No. 16/245,382
SEQUENCING-DIRECTED SELECTION OF TUMOR THERANOSTICS
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Abstract
The present disclosure relates to therapies for the treatment of tumor, autoimmune diseases, or other diseases. In some embodiments, the present disclosure can relate to subject-specific selection of humanized antibodies targeting clonal lineage specific marker proteins.
Claims (4)
1 . A humanized construct comprising:
a. a first domain having an affinity for a clonal lineage specific marker protein (CLSMP); and
b. a second domain having an affinity for an effector antigen selected from the group consisting of CD3, CD28, CTLA4, PD-1, IL-2R, and Fc receptor.
2 .- 127 . (canceled)
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 11, 2020
From: AFFIGEN, LLC
To: COLLINS, MIKE
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