IP Library Granted Patent US 10,508,981
Granted Patent B2
US 10,508,981 · App. 16/248,758 · Granted Dec 17, 2019

System and method for sensing and trapping nanoparticles with plasmonic nanopores

Inventors: Justus C Ndukaife (West Lafayette, IN); Alexandra Boltasseva (West Lafayette, IN); Agbai Nnanna (Crown Point, IN)
Assignee: Purdue Research Foundation
G01N15/00G02B5/008G21K1/006B01L3/502761B82Y20/00B82Y30/00G01N2015/0038G01N2015/0053
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Quick Facts
Patent No.
US 10,508,981
App. No.
16/248,758
Granted
Dec 17, 2019
Kind
B2
Abstract

An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the conductive transparent layer and the conductive film layer, and an electric field source connected between the transparent layer and the film layer.

Claims (18)

1. A particle sensor, comprising:

a conductive transparent layer;

a conductive film aperture layer mounted to a substrate, the aperture layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the transparent layer and the aperture layer, the nanoparticles functionalized with a target protein, the nanopores functionalized with an antibody of the target protein;

a light source configured to illuminate the nanopores to induce a flow of the nanoparticles towards the nanopores; and

an electric field source connected between the transparent layer and the aperture layer.

2. The apparatus of claim 1 , wherein the light source is a laser.

3. The apparatus of claim 1 , wherein the conductive transparent layer comprises indium tin oxide.

4. The apparatus of claim 1 , further comprising a metasurface lens which focuses the light source onto the nanopores.

5. The apparatus of claim 4 , wherein a diffraction grating is formed in the transparent layer.

6. The apparatus of claim 1 , wherein the nanoparticles comprise gold.

7. The apparatus of claim 1 , wherein the electric field source comprises an alternating current source.

8. The apparatus of claim 7 , wherein a frequency of the alternating current source is in the range of 5 KHz-100 KHz.

9. The apparatus of claim 1 , wherein the field produced by the electric field source is in the range of 40K-1 M volts per meter.

10. The apparatus of claim 1 , further comprising a random array of nanopores in the aperture layer separated from each other, wherein the random array of nanospores absorb broadband light to generate surface plasmons.

11. The apparatus of claim 1 , wherein the nanopore is surrounded by a bullseye grating to provide concentration of light to the nanopore and outcoupling of light from the nanopore to free space.

12. The apparatus of claim 1 , wherein the aperture layer comprises alternating layers of subwavelength metal and dielectric nanostructures.

13. The apparatus of claim 1 , wherein the aperture layer comprises alternating portions of subwavelength metal and dielectric nanostructures arranged configuration, each of said portions extending through the aperature layer thickness.

14. The apparatus of claim 1 , wherein each nanospore of the nanopores have a diameter in the range of 2 nm to 900 nm.

Assignments (1)
CONFIRMATORY LICENSE Recorded Mar 5, 2019
From: PURDUE UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 048509/0075 →
Continuity (3)
Division 15476868 · Mar 31, 2017
Provisional Application 62316558 · Mar 31, 2016
Related Publication 20190154558A1 · May 23, 2019