Pyrimidine compounds and pyrimido indole compounds and methods of use
The present invention discloses a compound comprising the formula: wherein R is hydrogen or an alkyl group having from one to ten carbon atoms, or a compound of the formula wherein the S is replaced by CH 2 or O, and optionally comprising a pharmaceutically acceptable salt or hydrate thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt or hydrate thereof.
1. A compound of the formula:
wherein R is selected from one of the following groups consisting of:
and optionally comprising a pharmaceutically acceptable salt or hydrate thereof.
2. A pharmaceutical composition comprising a therapeutically effective amount of a compound of the formula:
wherein R is selected from one of the following groups consisting of:
and optionally comprising a pharmaceutically acceptable salt or hydrate thereof.
3. The pharmaceutical composition of claim 2 comprising at least one pharmaceutical carrier.