IP Library › Granted Patent US 11,224,392
Granted Patent B2
US 11,224,392 · App. 16/259,449 · Granted Jan 18, 2022

Mapping disease spread

Inventor: William S. Krimsky (Forest Hill, MD)
Assignee: COVIDIEN LP
A61B6/466A61B5/0059A61B6/037A61B6/12A61B6/4417A61B6/487A61B8/0841A61B8/12A61B8/4245A61B8/4254A61B8/4416A61B8/463A61B8/466A61B8/5261G06T7/0014G06T7/149G16H50/50A61B8/085A61B10/04A61B2010/045G06T2207/10081G06T2207/20128G06T2207/30061
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Quick Facts
Patent No.
US 11,224,392
App. No.
16/259,449
Granted
Jan 18, 2022
Kind
B2
Abstract

Disclosed are systems and methods for mapping a patient's lymphatic system. An exemplary method includes generating a three-dimensional (3D) model of a bronchial network in the patient's chest, generating a lymphatic tree map by fitting a model lymph node map to the 3D model, receiving locations of a plurality of identified lymph nodes, updating the positions of lymph nodes on the lymphatic tree map, and displaying the updated lymphatic tree map.

Claims (29)

1. A method for mapping a patient's lymphatic system, the method comprising:

generating a three-dimensional (3D) model of a bronchial network in a chest of the patient based on first image data of the chest of the patient;

generating a lymphatic tree map by fitting a model lymph node map to the 3D model;

receiving locations of a plurality of identified lymph nodes;

updating the lymphatic tree map by correlating the locations of the plurality of identified lymph nodes with the lymphatic tree map;

displaying the updated lymphatic tree map;

receiving second image data of the chest of the patient;

identifying a radiopaque element injected into a target in the second image data;

determining a distribution path from the target based on the radiopaque element identified and the lymphatic tree map as updated;

identifying a sentinel lymph node based on the distribution path;

displaying the sentinel lymph node identified on the lymphatic tree map as updated;

identifying a lymph node in the distribution path a predetermined distance from the sentinel lymph node; and

displaying the lymph node identified on the lymphatic tree map as updated.

2. The method according to claim 1 , wherein the plurality of lymph nodes are identified based on image processing of the first image data.

3. The method according to claim 1 , wherein the lymph nodes are identified based on electromagnetic sensor (EM) data received from an EM sensor coupled to a tool being navigated about the chest.

4. The method according to claim 1 , wherein the lymph nodes are identified based on return signals received from a linear ultrasound scope.

5. The method according to claim 1 , further comprising identifying a lesion in the 3D model.

6. The method according to claim 5 , wherein the target is a lymph node proximate the identified lesion.

7. The method according to claim 1 , wherein the radiopaque element is one of:

radio-tagged whole blood from the patient;

a collagen tracer; and

a radiation tracer.

8. The method according to claim 1 , wherein the predetermined distance is at least about 5 cm.

9. The method according to claim 1 , wherein the predetermined distance is between about 7 cm and about 10 cm.

10. The method according to claim 1 , wherein the lymph node identified is a lymph node with at least three other lymph nodes between the lymph node identified and the sentinel lymph node.

11. The method according to claim 1 , further comprising:

determining areas to which spread may occur based on the sentinel lymph node identified and the distribution path; and

displaying the areas to which spread may occur on the lymphatic tree map as updated.

12. The method according to claim 1 , wherein the model lymph node map is International Association for the Study of Lung Cancer (IASLC) lymph node map.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 26, 2019
From: KRIMSKY, WILLIAM S.
To: COVIDIEN LP
Reel/Frame 048446/0001 →
Continuity (2)
Provisional Application 62624905 · Feb 1, 2018
Related Publication 20190231287A1 · Aug 1, 2019