Mapping disease spread
Disclosed are systems and methods for mapping a patient's lymphatic system. An exemplary method includes generating a three-dimensional (3D) model of a bronchial network in the patient's chest, generating a lymphatic tree map by fitting a model lymph node map to the 3D model, receiving locations of a plurality of identified lymph nodes, updating the positions of lymph nodes on the lymphatic tree map, and displaying the updated lymphatic tree map.
1. A method for mapping a patient's lymphatic system, the method comprising:
generating a three-dimensional (3D) model of a bronchial network in a chest of the patient based on first image data of the chest of the patient;
generating a lymphatic tree map by fitting a model lymph node map to the 3D model;
receiving locations of a plurality of identified lymph nodes;
updating the lymphatic tree map by correlating the locations of the plurality of identified lymph nodes with the lymphatic tree map;
displaying the updated lymphatic tree map;
receiving second image data of the chest of the patient;
identifying a radiopaque element injected into a target in the second image data;
determining a distribution path from the target based on the radiopaque element identified and the lymphatic tree map as updated;
identifying a sentinel lymph node based on the distribution path;
displaying the sentinel lymph node identified on the lymphatic tree map as updated;
identifying a lymph node in the distribution path a predetermined distance from the sentinel lymph node; and
displaying the lymph node identified on the lymphatic tree map as updated.
2. The method according to claim 1 , wherein the plurality of lymph nodes are identified based on image processing of the first image data.
3. The method according to claim 1 , wherein the lymph nodes are identified based on electromagnetic sensor (EM) data received from an EM sensor coupled to a tool being navigated about the chest.
4. The method according to claim 1 , wherein the lymph nodes are identified based on return signals received from a linear ultrasound scope.
5. The method according to claim 1 , further comprising identifying a lesion in the 3D model.
6. The method according to claim 5 , wherein the target is a lymph node proximate the identified lesion.
7. The method according to claim 1 , wherein the radiopaque element is one of:
radio-tagged whole blood from the patient;
a collagen tracer; and
a radiation tracer.
8. The method according to claim 1 , wherein the predetermined distance is at least about 5 cm.
9. The method according to claim 1 , wherein the predetermined distance is between about 7 cm and about 10 cm.
10. The method according to claim 1 , wherein the lymph node identified is a lymph node with at least three other lymph nodes between the lymph node identified and the sentinel lymph node.
11. The method according to claim 1 , further comprising:
determining areas to which spread may occur based on the sentinel lymph node identified and the distribution path; and
displaying the areas to which spread may occur on the lymphatic tree map as updated.
12. The method according to claim 1 , wherein the model lymph node map is International Association for the Study of Lung Cancer (IASLC) lymph node map.