IP Library › Granted Patent US 11,078,157
Granted Patent B1
US 11,078,157 · App. 16/262,281 · Granted Aug 3, 2021

Compound embodiments that release H2S by reaction with a reactive compound and methods of making and using the same

Inventors: Michael D. Pluth (Eugene, OR); Matthew M. Cerda (Eugene, OR)
Assignee: University of Oregon
C07C325/00C07C327/22C07C327/26G01N33/84
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Quick Facts
Patent No.
US 11,078,157
App. No.
16/262,281
Granted
Aug 3, 2021
Kind
B1
Abstract

Disclosed herein are embodiments of a donor compound that releases H 2 S by reacting with a reactive compound. The donor compound embodiments described herein can be used to deliver H 2 S to a subject or a sample and further can be used to administer therapeutic agents. The donor compound embodiments also can facilitate bioconjugation. Methods of making and using the donor compound embodiments also are disclosed.

Claims (2)

1. A compound, wherein the compound is

2. A pharmaceutical composition, comprising a compound according to claim 1 , and a pharmaceutically acceptable excipient.

Assignments (2)
CONFIRMATORY LICENSE Recorded Sep 20, 2021
From: UNIVERSITY OF OREGON
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 057542/0922 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 4, 2019
From: PLUTH, MICHAEL D.; CERDA, MATTHEW M.
To: UNIVERSITY OF OREGON
Reel/Frame 048250/0748 →
Continuity (1)
Provisional Application 62624609 · Jan 31, 2018