IP Library Granted Patent US 11,052,160
Granted Patent B2
US 11,052,160 · App. 16/264,296 · Granted Jul 6, 2021

Selective delivery molecules and methods of use

Inventors: Jesus Gonzalez (Carlsbad, CA); Junjie Liu (San Diego, CA)
Assignee: Avelas Biosciences, Inc.
A61K49/0056A61K47/60A61K47/64A61K47/65A61K49/0032A61K49/0054
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Quick Facts
Patent No.
US 11,052,160
App. No.
16/264,296
Granted
Jul 6, 2021
Kind
B2
Abstract

Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or tissue retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) cargo moieties (portion D A and D B ).

Claims (1)

1. A peptide according to Peptide P-16, having the structure:

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2023
From: AVELAS BIOSCIENCES, INC.
To: AVELAS (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC
Reel/Frame 064958/0678 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2023
From: AVELAS (ASSIGNMENT FOR THE BENEFIT OF CREDITORS), LLC
To: AVELAS ACQUISITION CORPORATION
Reel/Frame 064958/0732 →
RELEASE OF SECURITY INTEREST Recorded Oct 28, 2022
From: PACIFIC WESTERN BANK
To: AVELAS BIOSCIENCES, INC.
Reel/Frame 061576/0731 →
SECURITY INTEREST Recorded Sep 12, 2019
From: AVELAS BIOSCIENCES, INC.
To: PACIFIC WESTERN BANK
Reel/Frame 050361/0223 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: GONZALEZ, JESUS; LIU, JUNJIE
To: AVELAS BIOSCIENCES, INC.
Reel/Frame 048213/0591 →
Continuity (4)
Continuation 15685942 · Aug 24, 2017
Continuation 14764681
Provisional Application 61758680 · Jan 30, 2013
Related Publication 20190151481A1 · May 23, 2019