IP Library Granted Patent US 10,814,144
Granted Patent B2
US 10,814,144 · App. 16/294,707 · Granted Oct 27, 2020

Radiation treatment based on dose rate

Inventors: Deepak Khuntia (Los Altos, CA); Edward Vertatschitsch (San Carlos, CA); Eric Abel (San Jose, CA); Anthony Magliari (Newark, IL); Christel Smith (Santa Barbara, CA)
Assignee: Varian Medical Systems, Inc.
A61N5/1031A61N5/1043A61N5/1045A61N2005/1034A61N2005/1035A61N2005/1087
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Quick Facts
Patent No.
US 10,814,144
App. No.
16/294,707
Granted
Oct 27, 2020
Kind
B2
Abstract

A dose rate-volume histogram can be generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. The radiation treatment plan can be used as the basis for treating a patient using a radiation treatment system.

Claims (33)

1. A radiation treatment system, comprising:

a beam system that generates a beam;

a nozzle coupled to the beam system and that directs the beam to a target volume; and

a control system coupled to the beam system and to the nozzle, the control system comprising a computer system comprising a processor and a memory coupled to the processor;

wherein the memory stores a radiation treatment plan comprising a dose rate-volume histogram for the target volume, wherein the dose rate-volume histogram indicates a percentage of the target volume that receives a respective dose rate; and

wherein the beam system and the nozzle are controlled by the control system according to the radiation treatment plan.

2. The radiation treatment system of claim 1 , wherein the target volume comprises a plurality of sub-volumes, wherein the radiation treatment plan further comprises a dose rate-volume histogram for each sub-volume of the sub-volumes.

3. The radiation treatment system of claim 1 , wherein the radiation treatment plan further comprises a number of irradiations of the target volume, a duration of each of the irradiations, and a dose deposited in each of the irradiations.

4. The radiation treatment system of claim 3 , wherein the radiation treatment plan further comprises a period of time during which the irradiations are applied, and an interval of time between each period of irradiations.

5. The radiation treatment system of claim 1 , wherein the radiation treatment plan further comprises directions of the beam relative to the target volume, and a beam energy for the beam.

6. The radiation treatment system of claim 1 , wherein the beam comprises a type of beam selected from the group consisting of: proton; electron; photon; atom nuclei; and ion.

7. The radiation treatment system of claim 1 , wherein the radiation treatment plan further comprises isolines of dose rates relative to the target volume based on the dose rate-volume histogram.

8. The radiation treatment system of claim 1 , wherein the radiation treatment plan further comprises an irradiation time-volume histogram for the target volume, wherein the irradiation time-volume histogram indicates a percentage of the target volume that is irradiated for a respective length of time.

9. A method of using a radiation treatment system, the method comprising:

generating a beam with a beam system;

directing the beam at a target volume with a nozzle coupled to the beam system; and

controlling the beam with a control system comprising a computer system comprising a processor and a memory coupled to the processor, wherein said controlling is according to a radiation treatment plan stored in the memory, wherein the radiation treatment plan comprises a dose rate-volume histogram for the target volume, and wherein the dose rate-volume histogram indicates a percentage of the target volume that receives a respective dose rate.

10. The method of claim 9 , wherein the target volume comprises a plurality of sub-volumes, wherein the radiation treatment plan further comprises a dose rate-volume histogram for each sub-volume of the sub-volumes.

11. The method of claim 9 , wherein the radiation treatment plan further comprises a number of irradiations of the target volume, a duration of each of the irradiations, and a dose deposited in each of the irradiations, a period of time during which the irradiations are applied, an interval of time between each period of irradiations, directions of the beam relative to the target volume, and a beam energy for the beam.

12. The method of claim 9 , wherein the beam comprises a type of beam selected from the group consisting of: proton; electron; photon; atom nuclei; and ion.

13. The method of claim 9 , wherein the radiation treatment plan further comprises isolines of dose rates relative to the target volume based on the dose rate-volume histogram.

14. The method of claim 9 , wherein the radiation treatment plan further comprises an irradiation time-volume histogram for the target volume, wherein the irradiation time-volume histogram indicates a percentage of the target volume that is irradiated for a respective length of time.

15. A method of using a radiation treatment system, the method comprising:

generating a beam with a beam system;

directing the beam at a target volume with a nozzle coupled to the beam system, wherein the target volume comprises a plurality of sub-volumes;

monitoring, with a control system coupled to the beam system, values of parameters, the values comprising a number of irradiations of each sub-volume of the plurality of sub-volumes, a duration of each of the irradiations for said each sub-volume, and a dose deposited in said each sub-volume, that result from said directing;

determining a dose rate for said each sub-volume using the values of the parameters; and

determining a dose rate-volume histogram for the target volume using the dose rate for said each sub-volume, wherein the dose rate-volume histogram indicates a percentage of the target volume that receives a respective dose rate.

16. The method of claim 15 , further comprising determining a dose rate-volume histogram for said each sub-volume.

17. The method of claim 15 , wherein the values of the parameters further comprise a period of time during which the irradiations are applied, an interval of time between each period of irradiations, directions of the beam relative to the target volume, and a beam energy for the beam.

18. The method of claim 15 , wherein the beam comprises a type of beam selected from the group consisting of: proton; electron; photon; atom nuclei; and ion.

19. The method of claim 15 , further comprising determining isolines of dose rates relative to the target volume based on the dose rate-volume histogram.

20. The method of claim 15 , further comprising determining an irradiation time-volume histogram for the target volume, wherein the irradiation time-volume histogram indicates a percentage of the target volume that is irradiated for a respective length of time.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 6, 2024
From: VARIAN MEDICAL SYSTEMS, INC.
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 066668/0713 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 25, 2019
From: KHUNTIA, DEEPAK; VERTATSCHITSCH, EDWARD; ABEL, ERIC; MAGLIARI, ANTHONY; SMITH, CHRISTEL
To: VARIAN MEDICAL SYSTEMS, INC
Reel/Frame 049000/0557 →
Continuity (1)
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