Activated release of target material trapped in anisotropic fluids
Systems and methods for the controlled release of a guest composition that is sequestered within a host composition made up of an anisotropic fluid are disclosed. The guest composition is immiscible in the host composition, thus forming an interface between the compositions upon which elastic repulsion forces act to prevent the release of the guest composition from the host composition. The disclosed systems and methods work by changing the elastic repulsion forces and/or introducing one or more counter forces such that the elastic repulsion forces are no longer sufficient to prevent release of the guest composition. Exemplary methods include mechanically changing the host material (e.g., changing its temperature) or inducing a chemical (e.g., electrostatic) attraction sufficient to overcome the elastic repulsion forces. The disclosed systems and methods can be used for a variety of applications requiring “on-demand” delivery of a chemical composition.
1. A system for the controlled release of a guest composition sequestered within a host composition, the system comprising:
(a) a host composition comprising an anisotropic fluid, wherein the host composition does not comprise a lyotropic liquid crystal;
(b) a guest composition sequestered within the host composition, wherein the guest composition is in a form of a plurality of liquid droplets, the guest composition is immiscible or insoluble in the host composition, and the guest composition forms an interface with the host composition upon which elastic repulsion forces act to prevent release of the guest composition from the host composition; and
(c) a composition in fluid communication with the host composition, the composition (c) capable of changing the elastic repulsion forces, introducing one or more counter forces, or both, such that the elastic repulsion forces do not act to prevent release of the guest composition from the host composition.
2. The system of claim 1 , wherein the liquid droplets of the plurality of liquid droplets are aqueous droplets.
3. The system of claim 2 , wherein the aqueous droplets comprise amphiphiles positioned at the interface.
4. The system of claim 1 , wherein the anisotropic fluid is a liquid crystal.
5. The system of claim 4 , wherein the liquid crystal is a thermotropic liquid crystal.
6. The system of claim 1 , wherein the liquid droplets of the plurality of liquid droplets are aqueous droplets comprising amphiphiles positioned at the interface and the anisotropic fluid is a thermotropic liquid crystal.
7. The system of claim 1 , wherein the composition (c) is positioned adjacent to and in contact with the host composition.
8. The system of claim 1 , wherein the composition (c) comprises one or more of a charged molecule, an amphiphile, a polymer, a solute that is miscible in the host composition, a pH-changing agent, motile bacteria, and a light-sensitive compound.
9. The system of claim 1 , consisting of the host composition, the guest composition, and the composition (c).
10. The system of claim 9 , wherein the liquid droplets of the plurality of liquid droplets are aqueous droplets comprising amphiphiles positioned at the interface, the anisotropic fluid is a thermotropic liquid crystal, and the composition (c) is positioned adjacent to and in contact with the host composition.
11. The system of claim 1 , further comprising (d) a device capable of changing the elastic repulsion forces, introducing the one or more counter forces, or both, such that the elastic repulsion forces do not act to prevent release of the guest composition from the host composition.
12. The system of claim 11 , wherein the device (d) is selected from a device capable of changing a temperature of the host composition, a source of an electric field or a magnetic field, and a device capable of inducing a shear stress at the interface.
13. The system of claim 12 , consisting of the host composition, the guest composition, the composition (c), and the device (d).
14. The system of claim 13 , wherein the liquid droplets of the plurality of liquid droplets are aqueous droplets comprising amphiphiles positioned at the interface, the anisotropic fluid is a thermotropic liquid crystal, and the composition (c) is positioned adjacent to and in contact with the host composition.
15. A method of using the system of claim 1 , the method comprising changing the elastic repulsion forces, introducing the one or more counter forces, or both, by inducing the fluid communication between the composition (c) and the host composition to release the guest composition from the host composition.
16. A system for the controlled release of a guest composition sequestered within a host composition, the system comprising:
(a) a host composition comprising an anisotropic fluid, wherein the host composition does not comprise a lyotropic liquid crystal;
(b) a guest composition sequestered within the host composition, wherein the guest composition is in a form of a plurality of liquid droplets, the guest composition is immiscible or insoluble in the host composition, and the guest composition forms an interface with the host composition upon which elastic repulsion forces act to prevent release of the guest composition from the host composition; and
(c) a device capable of changing the elastic repulsion forces, introducing one or more counter forces, or both, such that the elastic repulsion forces do not act to prevent release of the guest composition from the host composition.
17. The system of claim 16 , wherein the device (c) is selected from a device capable of changing a temperature of the host composition, a source of an electric field or a magnetic field, and a device capable of inducing a shear stress at the interface.
18. The system of claim 17 , the system consisting of the host composition, the guest composition, and the device (c).
19. The system of claim 18 , wherein the liquid droplets of the plurality of liquid droplets are aqueous droplets comprising amphiphiles positioned at the interface and the anisotropic fluid is a thermotropic liquid crystal.
20. A method of using the system of claim 16 , the method comprising changing the elastic repulsion forces, introducing the one or more counter forces, or both, by operating the device (c) to release the guest composition from the host composition.