IP Library › Granted Patent US 10,987,374
Granted Patent B2
US 10,987,374 · App. 16/322,626 · Granted Apr 27, 2021

Composition for promoting production of immunostimulatory factor

Inventors: Takashi Fujita (Kyoto, JP); Hiroki Kato (Kyoto, JP); Tetsuya Nakazaki (Kyoto, JP)
Assignee: KYOTO UNIVERSITY
A61K31/713A23L33/13A61K9/0073A61K35/76A61K36/48A61K36/81A61K36/899A61K39/39A61P31/12A61P31/14A61P35/00A61P37/04Y02A50/30
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Quick Facts
Patent No.
US 10,987,374
App. No.
16/322,626
Granted
Apr 27, 2021
Kind
B2
Abstract

According to the present invention, various diseases, such as viral diseases, cancer, and multiple sclerosis, can be prevented and improved by using an immunostimulatory factor production-promoting composition comprising genomic double-stranded RNA of a plant-derived endornavirus.

Claims (14)

1. A method for promoting immunostimulatory factor production in an animal or human, comprising administering a composition comprising a genomic double-stranded RNA of a plant-derived endornavirus to the animal or human.

2. The method according to claim 1 , wherein the plant is a capsicum plant, a rice plant, or a Vicia plant.

3. The method according to claim 1 , wherein the genomic double-stranded RNA has a length of 8 to 20 kbp.

4. The method according to claim 1 , wherein the genomic double-stranded RNA is linear.

5. The method according to claim 1 , wherein the composition is a pharmaceutical composition.

6. The method according to claim 1 , wherein the composition is an intranasal preparation.

7. The method according to claim 1 , wherein the composition is an oral preparation.

8. The method according to claim 1 , wherein the composition is a food composition.

9. The method according to claim 1 , wherein the animal or human has a viral infection.

10. The method according to claim 9 , wherein the animal or human has an RNA viral infection.

11. The method according to claim 1 , wherein the composition is used as an adjuvant.

12. The method according to claim 1 , wherein the animal or human has cancer.

13. The method according to claim 1 , wherein the plant is Capsicum annuum Kyousuzu.

14. The method according to claim 1 , wherein the plant is Oryza sativa Koshihikari.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2019
From: FUJITA, TAKASHI; KATO, HIROKI; NAKAZAKI, TETSUYA
To: KYOTO UNIVERSITY
Reel/Frame 049362/0228 →
Priority Claims (2)
JP JP2016-151836 · Aug 2, 2016 · national
JP JP2017-021008 · Feb 8, 2017 · national
Continuity (1)
Related Publication 20190290674A1 · Sep 26, 2019