IP Library Granted Patent US 10,406,193
Granted Patent B2
US 10,406,193 · App. 16/326,562 · Granted Sep 10, 2019

Composition for topical application with antifungal activity

Inventor: Giorgio Panin (Rovigo, IT)
Assignee: BIO.LO.GA. S.R.L.
A61K36/61A61K9/0014A61K9/06A61K31/355A61K36/53A61K36/752A61P31/10
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Quick Facts
Patent No.
US 10,406,193
App. No.
16/326,562
Granted
Sep 10, 2019
Kind
B2
Abstract

A composition for topical application with antifungal activity, containing Melaleuca alternifolia essential oil, oregano essential oil, lime essential oil and an ester of vitamin E is enclosed. Vitamin E acetate, n-propionate or linoleate, and is preferably alpha-tocopheryl acetate; preferably, these oils constitute at least 3% by weight of the composition and each of them constitutes at least 1% by weight of the composition; preferably, the composition contains from 10% to 97% of the ester of vitamin E and can consist of the three aforementioned essential oils and the vitamin E ester; alternatively, the composition can be in the form of hydrophobic gel, containing 10 to 50% of the ester of vitamin E, 20 to 60% of a vegetable butter or wax, from 10 to 30% of triglyceride of caprylic and capric acid and from 5 to 20% of a gelling agent for lipids and at least 3% of the aforementioned essential oils, each of which constitutes at least 1% by weight of the composition.

Claims (11)

1. A topical anti-fungal composition consisting essentially of therapeutically effective amounts of melaleuca alternifolia essential oil, oregano essential oil, lime essential oil am a component selected from the group consisting of vitamin E acetate, n-propionate and linoleate.

2. The composition of claim 1 , wherein the total of said essential oils of Melaleuca alternifolia , oregano and lime constitute at least 3% by weight of the total composition and each of them individually constitutes at least 1% by weight of the total composition.

3. The composition of claim 2 , containing from 10% to 97% of said component in the total composition.

4. The composition of claim 3 , wherein said component is alpha-tocopheryl acetate.

5. The composition of claim 3 , consisting of Melaleuca alternifolia essential oil, oregano essential oil, lime essential oil and said component.

6. The composition of claim according to claim 5 , consisting of 95%-97% alpha-tocopheryl acetate and 3-5% of said essential oils, each one of said essential oils constituting at least 1% by weight on the weight of the total composition.

7. The composition of claim 2 , in the form of hydrophobic gel, containing 10 to 50% of said component, 20 to 60% of a vegetable butter or wax, from 10 to 30% triglyceride of caprylic and capric acid and from 5 to 20% of a gelling agent selected from the group consisting of triglyceride of palmitic and stearic acid, Sorbitan Olivate and Silica.

8. The composition of claim 7 , further consisting of one or more of hydrogenated castor oil, phytosterols and ceramide.

9. The composition of claim 8 , wherein said component is alpha-tocopheryl acetate, said vegetable butter is shea butter and said ceramide is ceramide-NP.

10. The composition of claim 1 , wherein said component is alpha-tocopheryl acetate.

11. The composition according to claim 5 , wherein said component is alpha-tocopheryl acetate.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 14, 2022
From: BIO.LO.GA. S.R.L.
To: HULKA S.R.L.
Reel/Frame 059364/0206 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2019
From: PANIN, GIORGIO
To: BIO.LO.GA. S.R.L.
Reel/Frame 048561/0547 →
Priority Claims (1)
IT 102016000109403 · Oct 28, 2016 · national
Continuity (1)
Related Publication 20190224263A1 · Jul 25, 2019