Method for producing N-methyl-para-anisidine
View Patent ↗The invention relates to chemical engineering processes, and more particularly to liquid-phase catalytic methods for producing, in the presence of hydrogen, alkylated para-anisidine for use as a chemical substance or as a gasoline additive for increasing the octane rating of a gasoline. The technical result of the claimed group of inventions is an increase in the yield of N-methyl-para-anisidine and a decrease in the yield of a dimethyl derivative. A method for producing N-methyl-para-anisidine in a liquid phase includes alkylating para-anisidine with formalin as they are separately, simultaneously fed into a mixer disposed in a reactor, directly upstream of a catalytic reduction zone, thus producing an intermediate azomethine, and subsequently reducing same on a hydrogenation catalyst at a temperature of 20-120° C. in an environment of hydrogen at elevated pressure, and then isolating the target product, N-methyl-para-anisidine.
1. A method for producing N-methyl-para-anisidine in a liquid phase, comprising alkylating para-anisidine with formalin as they are separately, simultaneously fed into a mixer disposed in a reactor, directly upstream of a catalytic reduction zone, thus producing an intermediate azomethine-4-methoxy-(N-phenylmethanimine), and subsequently reducing said intermediate on a hydrogenation catalyst at a temperature of 20-120° C., in an environment of hydrogen at elevated pressure, and then separating the target product, N-methyl-para-anisidine, wherein para-anisidine is used in the form of a solution in a solvent selected from the group: ethanol, methanol, isopropanol.
2. The method according to claim 1 , wherein the alkylation is carried out in a batch mode.
3. The method according to claim 1 , wherein the alkylation is carried out on in a continuous mode.
4. The method according to claim 1 , wherein stabilizers are used during the alkylation in the form of tertiary aliphatic amines, wherein said stabilizers are used in the amount of 5-10 mol. % of the para-anisidine load.
5. The method according to claim 4 , wherein tertiary aliphatic amines are selected from the group: triethylamine, tetramethylethylenediamine, diisopropylethylamine, dimethylbenzylamine, diazabicyclooctane, tripropylamine, aqueous solution of trimethylamine.
6. The method according to claim 4 , wherein the stabilizer is introduced into the reactor during loading of the hydrogenation catalyst and/or during supply of para-anisidine.
7. The method according to claim 1 , wherein the hydrogenation catalyst is used in the form of a suspension or in the form of a fixed layer.
8. The method according to claim 1 , wherein the separation of N-methyl-para-anisidine is carried out by fractional distillation.